Actively Recruiting
Researching Economical Adjuvants to Cancer Therapy
Led by Florida State University · Updated on 2025-12-26
60
Participants Needed
1
Research Sites
202 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if beta-glucan (a dietary fiber) improves the function of the immune system in adults. It will also tell the investigators if combining beta-glucan with single bouts of exercise provides additional benefit. The main questions it aims to answer are: 1. Does beta-glucan change the ability of immune cells to recognize cancer cells? 2. Does exercise change the type of immune cells in the blood? Researchers will compare beta-glucan to a placebo (a look-alike substance with no effect) to see if beta-glucan could improve immune function against cancer. Participants will: 1. Take beta-glucan or a placebo daily for 4 weeks. 2. Visit the laboratory for three exercise tests. 3. Provide blood samples so researchers can study immune system cells.
CONDITIONS
Official Title
Researching Economical Adjuvants to Cancer Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Physically fit enough to engage in maximal exercise
- Adults aged 18 to 45 years
You will not qualify if you...
- Body mass index (BMI) over 40 kg/m2
- Stage 2 hypertension (140/90 mmHg)
- Type I or II diabetes
- Autoimmune diseases
- Overt cardiovascular, respiratory, or neurological diseases (e.g., previous heart attack, pacemaker, heart failure, asthma)
- Hormone replacement therapy (e.g., androgens, estrogens)
- Daily medications affecting immune function (e.g., beta blockers, NSAIDs, corticosteroids, allergy medications)
- Current antibiotic use
- Heavy alcohol use (more than 2 drinks per day)
- Tobacco use within the last 6 months
- Adults unable to consent
- Individuals who are not adults (infants, children, teenagers)
- Self-reported pregnancy
- Prisoners
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Institute of Sports Sciences and Medicine
Tallahassee, Florida, United States, 32306
Actively Recruiting
Research Team
K
Kyle A Smith, PhD, RD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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