Actively Recruiting
Researching Heat and Yoga for Mood Enhancement
Led by Massachusetts General Hospital · Updated on 2025-11-13
120
Participants Needed
2
Research Sites
74 weeks
Total Duration
On this page
Sponsors
M
Massachusetts General Hospital
Lead Sponsor
T
Tiny Blue Dot Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will examine how doing heated yoga or non-heated yoga affects depression.
CONDITIONS
Official Title
Researching Heat and Yoga for Mood Enhancement
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 65 years
- Able to provide consent
- Able to read and understand English
- PHQ-9 score between 10 and 20 indicating moderate depressive symptoms
- Completed waiver for the community-based yoga studio before enrolling
You will not qualify if you...
- Bone fracture or joint surgery within the past 6 months
- Unable to walk freely or without difficulty
- Severe heart failure or lung disease
- Endorsement of any item on the Physical Activity Readiness Questionnaire (PAR-Q+) without physician approval
- No physician responsible for medical care
- Pregnant or planning to become pregnant
- More than 6 yoga classes attended in the past 6 months
- Active suicidal thinking as indicated by PHQ-9 and C-SSRS responses
- Reported manic symptoms with Altman Self-Rating Mania Scale score 6 or higher
- Use of medications that increase dehydration risk (e.g., lithium, antipsychotics, insulin-dependent)
- Active eating or substance use disorders within the past 12 months
- Antidepressant or psychiatric medication changes less than 8 weeks or 4 weeks prior to screening
- Psychotherapy initiated within the past 3 months
- Must keep psychiatric medications and psychotherapy stable during the study
- Psychiatric hospitalization within the past year
- Neurological disorders impacting participation or safety
- Current active ketamine, ECT, or TMS treatments
- Unable to follow study procedures or travel to yoga studios
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Orange Door Collaborative
Cambridge, Massachusetts, United States, 02139
Actively Recruiting
2
Breathe Yoga Studio
Cambridge, Massachusetts, United States, 02142
Actively Recruiting
Research Team
M
Maren Nyer, PhD
CONTACT
L
Louisa Sylvia, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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