Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
NCT06278506

Resection or Ablation of Small Kidney Tumors

Led by Karolinska University Hospital · Updated on 2024-02-26

300

Participants Needed

1

Research Sites

721 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Ablative treatments are believed to have a lower rate of complications, shorter hospital stays, and fewer interventions with benign PAD compared to partial nephrectomies in small kidney cancer lesions. The purpose of the study is to compare complications, the frequency of residual tumors, impact on kidney function, differences in quality of life, and health economic factors in a randomised study. We will also compare the oncological outcomes, including survival and recurrence of kidney cancer.

CONDITIONS

Official Title

Resection or Ablation of Small Kidney Tumors

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 - 99 years
  • Patient suitable based on clinical status for both ablative treatment and surgery
  • Primary kidney tumor
  • Tumor size �3 cm or less
  • Clinical stage of the tumor T1a (no macroscopic vascular or extrarenal invasion)
  • Tumor location suitable for both ablative treatment and resection
  • Absence of radiological signs of metastasis
  • Biopsy with malignant pathological analysis (PAD)
  • ISUP grade I-III
Not Eligible

You will not qualify if you...

  • Radiological signs of metastasis
  • Synchronous kidney tumors
  • ISUP grade IV or sarcomatoid growth in the biopsy
  • Other metastasized cancer in the last 5 years
  • Patient unable to make an informed decision to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Karolinska University Hospital

Stockholm, Sweden, 14186

Actively Recruiting

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Research Team

A

Anders Kjellman, MD, PhD

CONTACT

P

Per-Olof Lundgren, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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