Actively Recruiting
Resilience in Adolescent Development
Led by University of Texas Southwestern Medical Center · Updated on 2025-05-06
1500
Participants Needed
1
Research Sites
850 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
RAD is a 10-year natural history, longitudinal, prospective assessment study of a cohort of 2,500 participants (ages 10-24 years) that will help uncover the socio-demographic, lifestyle, clinical, psychological, and neurobiological factors that contribute to resilience among children, adolescents, and young adults at-risk for mood and anxiety disorders. As this is an exploratory study, we will assess a comprehensive panel of carefully selected participant specific parameters, including socio-demographic, life habits, clinical, biological, behavioral, neurophysiological, and neuroimaging. The study is designed to observe and collect factors associated with resilience in a non-invasive fashion; no interventions or treatments will be conducted during the project. Assessments will be conducted up to 4 times per year for up to 10 years, as well as a baseline visit. Study visits will be conducted in person whenever feasible but may be completed by phone/mail/computer, if an in-person visit is not possible.
CONDITIONS
Official Title
Resilience in Adolescent Development
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Youth aged 10-24, male and female of all races and ethnicity
- Able to speak, read, and understand English; parents/guardians may speak English or Spanish for consent
- Adults 18 and older must provide written informed consent
- Youth under 18 require parent/guardian consent and youth assent
- Ability to complete clinical and neuropsychological tests
- Must be either at risk for mood disorder (personal or family history as defined) or a healthy individual with no psychiatric diagnoses or family history of mood disorder
You will not qualify if you...
- Unable to provide informed consent or assent
- Non-English speaking participants
- Diagnosis of psychotic disorders including mood disorder with psychotic features, schizophrenia, or schizoaffective disorder
- PHQ-9 score of 10 or greater
- Unable to provide stable home address and contact information
- Any condition that could interfere with study participation or assessments, including cognitive impairment, unstable medical condition, intoxication, or active psychosis
- Healthy controls with any history of mood disorder or personal/family history of other mental health disorders
- Participants who develop depression during study follow-up will continue in the study
AI-Screening
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Trial Site Locations
Total: 1 location
1
UT Southwestern Medical Center
Dallas, Texas, United States, 75390
Actively Recruiting
Research Team
A
Afrida Khurshid, BA
CONTACT
S
Sangita Sethuram, MBA, CCRP
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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