Actively Recruiting
Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial
Led by Dana-Farber Cancer Institute · Updated on 2026-02-19
45
Participants Needed
1
Research Sites
258 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research is to determine whether a virtually supervised resistance exercise (RE) intervention combined with protein supplementation (PS) is feasible in pancreatic cancer patients initiating chemotherapy and if it will improve skeletal muscle mass. The names of the study interventions involved in this study are: * Resistance training and protein supplement intake (RE + PS) * Resistance training (RE) * Attention control (AC), home-based stretching
CONDITIONS
Official Title
Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Non-metastatic pancreatic cancer patients starting neoadjuvant chemotherapy
- Ability to understand and willing to sign informed consent
- Age 18 years or older
- Speak English or Spanish
- Able to provide physician clearance for exercise
- Free from cardiovascular, respiratory, musculoskeletal disease or joint problems preventing moderate activity
- Currently perform 60 minutes or less of structured moderate or vigorous exercise per week
- No smoking during the previous 12 months
- Willing to travel to Dana-Farber Cancer Institute for assessments
You will not qualify if you...
- Uncontrolled illnesses including active infection, uncontrolled diabetes, hypertension, or thyroid disease
- Receiving other investigational agents
- Having other active cancers
- Metastatic disease
- History of musculoskeletal, cardiorespiratory, or neurological diseases preventing exercise
- Expected to receive other cancer treatments during the study
- Participates in more than 60 minutes of structured moderate or vigorous exercise per week
- Current smoker
- Unable to comply with safety monitoring
- Unable to travel to Dana-Farber Cancer Institute for assessments
- Pregnant due to unknown effects of exercise on fetus
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
C
Christina M Dieli-Conwright, PhD, MPH
CONTACT
C
Christina M Dieli-Conwright, PhD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
3
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