Actively Recruiting
Resistance Exercise and Creatine in Colorectal Cancer
Led by University of South Carolina · Updated on 2024-05-21
40
Participants Needed
1
Research Sites
80 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
skeletal muscle mass and function, is prevalent in up to 60% of colorectal cancer patients. This condition arises from a combination of factors such as aging, inactivity, treatment side effects, malnutrition, tumor burden, and inflammation. Given this complexity, singular interventions may not be sufficient to address sarcopenia in this group. Creatine monohydrate, a compound vital for energy during exercise, has been extensively researched and proven safe and effective across various demographics, including older adults and clinical populations. Studies show that creatine enhances benefits from resistance training, indicating potential to counter muscle mass and function decline post-cancer treatment. This study aims to assess the feasibilty of combining creatine supplementation with resistance training versus resistance training alone in sarcopenic colorectal cancer survivors. A randomized controlled pilot trial will compare a 10-week program of resistance exercise plus creatine (EXSUPP) with resistance exercise alone (EXPLA), each with 20 participants.
CONDITIONS
Official Title
Resistance Exercise and Creatine in Colorectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals at least 12 months post treatment for colorectal cancer
- Age over 18 years
You will not qualify if you...
- Currently receiving active cancer treatment
- Any contraindication to exercise participation
- Participating in structured resistance exercise 2 or more times per week for the past 6 months
- Taking creatine supplements within 4 weeks prior to the study
- Taking medications that may alter body composition such as metformin or corticosteroids
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of South Carolina
Columbia, South Carolina, United States, 29201
Actively Recruiting
Research Team
C
Ciaran Fairman
CONTACT
A
Alex Brooks
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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