Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06374108

Resistance Training and Corticospinal Excitability in Multiple Sclerosis

Led by University of Aarhus · Updated on 2024-12-11

54

Participants Needed

2

Research Sites

108 weeks

Total Duration

On this page

Sponsors

U

University of Aarhus

Lead Sponsor

A

Aarhus University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS). A total of 54 pwMS will be enrolled and randomized into 1 of 3 groups: high dose resistant training (RT), low dose RT, and waitlist control.

CONDITIONS

Official Title

Resistance Training and Corticospinal Excitability in Multiple Sclerosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age ≥ 18 years
  • MS diagnosis according to the McDonald diagnostic criteria
  • Shows impairments in walking capacity
  • Ability to self transport to test and exercise
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Neurological or other comorbidities that affects the nervous system
  • Relapse within the past 2 months
  • Pacemaker or metallic implants
  • Hypertension (medically unregulated)
  • Participation in structured RT over the past 3 months (≥ 2 sessions/week).

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Department of Public Health

Aarhus, Central Jutland, Denmark, 8000

Actively Recruiting

2

Department of Nutrition, Exercise and Sports, University of Copenhagen

Copenhagen, Copenhagen N, Denmark, 2200

Actively Recruiting

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Research Team

L

Lars Hvid, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Resistance Training and Corticospinal Excitability in Multiple Sclerosis | DecenTrialz