Actively Recruiting

Phase Not Applicable
Age: 50Years +
All Genders
Healthy Volunteers
NCT06185010

Resistance Training to Individuals for Cognitive Impairment With Dementia

Led by University of Beira Interior · Updated on 2024-08-06

80

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

Sponsors

U

University of Beira Interior

Lead Sponsor

R

Research Center in Sports Sciences, Health Sciences and Human Development

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. First the investigators will analyze the effects of a single resistance training session (acute effects) with one and three sets on hemodynamic and physical performance in individuals with mild cognitive impairment. After, the investigators will analyze the effects of an 8-week resistance training program with one or three sets on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. The investigators hypothesize that a single resistance training session of one or three sets will increase the acute hemodynamic and physical performance stress in individuals with mild cognitive impairment, although with a higher magnitude in the session with three sets. Furthermore, we hypothesize that eight weeks of resistance training with one or three sets will induce similar improvements in cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment.

CONDITIONS

Official Title

Resistance Training to Individuals for Cognitive Impairment With Dementia

Who Can Participate

Age: 50Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of mild cognitive impairment
  • Short Physical Performance Battery (SPPB) score of 3 points or higher
  • Willingness to participate in the interventions and collaborate with the research team
  • Ability to provide informed consent (oral or written)
Not Eligible

You will not qualify if you...

  • Severe dementia
  • Severe health conditions that affect participation in the intervention
  • Color blindness
  • Fractures within the last three months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Beira Interior

Covilha, Portugal

Actively Recruiting

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Research Team

N

Nuno Fonseca, Master's

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

PREVENTION

Number of Arms

5

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