Actively Recruiting

Phase 4
Age: 18Years - 75Years
All Genders
NCT07249788

Resmiterom Efficacy & Safety in Patients With MASH

Led by Nabiqasim Industries (Pvt) Ltd · Updated on 2025-12-03

165

Participants Needed

1

Research Sites

62 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Phase 4 clinical trial study aims to further evaluate the safety and therapeutic efficacy of Resmetirom in Pakistani patients with fibroscan proven MASH.

CONDITIONS

Official Title

Resmiterom Efficacy & Safety in Patients With MASH

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 75 years
  • At least one metabolic comorbidity such as type 2 diabetes, obesity, dyslipidemia, or hypertension
  • Clinical diagnosis of MASH using at least one of the following: liver stiffness measurement (LSM)  8.5 kPa, FAST score  0.67, FibroScan CAP  275 dB/m, or FIB-4 > 1.3
Not Eligible

You will not qualify if you...

  • History of drug addiction or alcoholism
  • Cirrhosis or decompensated liver disease
  • Chronic viral hepatitis (HBV, HCV)
  • Major adverse cardiovascular events including myocardial infarction, stroke, or pulmonary embolism
  • Pregnant or lactating women
  • Concurrent use of other investigational drugs
  • History of other liver diseases (viral, autoimmune, drug-induced, alcoholic)
  • Previous use of Resmetirom in the last 6 months
  • Significant renal impairment with eGFR < 30

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Liver transplant center, Holy family hospital

Rawalpindi, Punjab Province, Pakistan

Actively Recruiting

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Research Team

H

Hussain B Abidi, MBBS, MBA, CRCP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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