Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05030207

Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy

Led by University of Sydney · Updated on 2025-04-04

30

Participants Needed

1

Research Sites

80 weeks

Total Duration

On this page

Sponsors

U

University of Sydney

Lead Sponsor

W

Western Sydney Local Health District

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study does not involve a therapeutic intervention as standard radiation therapy treatment will be prescribed. This study involves one additional 4DCT scan (i.e. the Real-Time Gated 4DCT scan) acquired immediately before or following the conventional 4DCT scan. This will take place on the day of the patient's treatment simulation, as per the current standard of care. The scanning sequence (i.e. conventional first versus gated first) will be randomised. The Real-Time Gated 4DCT is anticipated to take longer than the conventional 4DCT scan, due to its gated (beam-pause) nature. However, upper limits for timing will be implemented in the software, and the scan aborted for highly erratic breathing traces that would not benefit from a Real-Time Gated 4DCT scan.

CONDITIONS

Official Title

Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Ability to give informed consent
  • Diagnosed with lung cancer and scheduled for radiation therapy
  • Radiation therapy treatment plan includes acquisition of a 4DCT scan
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Patients younger than 18 years
  • Patients unable to tolerate extra time on the CT scanner for an additional scan according to their physician

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Blacktown Hospital

Blacktown, New South Wales, Australia, 2148

Actively Recruiting

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Research Team

S

Shona J Silvester, MMedSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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