Actively Recruiting

Age: 20Years - 39Years
FEMALE
NCT06874478

Respiratory Distress and Elective Cesarean Section at Term

Led by Assiut University · Updated on 2025-05-28

210

Participants Needed

1

Research Sites

134 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cesarean section is a life-saving surgical operation for women and their newborns. In Egypt, caesarean sections are over-utilized. The rate increased from 27.6 % in 2008 to 51.8 % in 2014, reaching 72.2 % in 2021. Cesarean section has been associated with an increased risk of adverse respiratory outcomes in newborns. Studies have shown a higher risk of neonatal respiratory distress syndrome in babies born by elective cesarean section, especially at 37 and 38 weeks' gestation. Neonatal respiratory distress syndrome is one of the leading causes of neonatal morbidity and mortality. Many non-invasive tools have been used to predict the risk of neonatal respiratory distress syndrome. Most of these studies assessed the predictors of neonatal respiratory distress syndrome in low birth or preterm fetuses, and none of them talked about neonatal respiratory distress syndrome with term fetuses. Doppler velocimetry provides a simple and non-invasive method to assess the fetal pulmonary circulation. Pulmonary Doppler velocimetry is used to determine lung maturity in complicated pregnancies. The magnitude of neonatal respiratory distress syndrome among term neonates depends on the availability of medical services and the number of trained medical personnel. So, there is a need to assess the rate and predictors of eonatal respiratory distress syndrome among low-risk term fetuses delivered by Cesarean section to give attention and appropriate intervention for these predictors to decrease the morbidity and mortality associated with eonatal respiratory distress syndrome.

CONDITIONS

Official Title

Respiratory Distress and Elective Cesarean Section at Term

Who Can Participate

Age: 20Years - 39Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Maternal age of 20-39 years
  • Women with singleton pregnancy at or beyond 37 weeks
  • Pregnant women who received corticosteroids to enhance lung maturity and will have elective cesarean section within 1 week after corticosteroid administration
Not Eligible

You will not qualify if you...

  • Women with oligohydramnios or polyhydramnios
  • Women with underlying diseases requiring corticosteroids
  • Pregnant women with medical disorders such as hypertension, diabetes, kidney diseases, antiphospholipid syndrome, intrauterine growth restriction, preterm premature rupture of membrane, placenta previa, antepartum hemorrhage, or on anticoagulants
  • Women with confirmed fetal malformation
  • Women who refuse to participate

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Woman's Health Hospital - Assiut university

Asyut, Egypt, 71111

Actively Recruiting

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Research Team

M

Mohammed K Ali, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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