Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT06217276

Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation

Led by Istanbul Medipol University Hospital · Updated on 2025-05-01

30

Participants Needed

1

Research Sites

103 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In our study, changes in vastus lateralis muscle oxygenation will be evaluated with the Moxy device, a functional infrared oxygen measurement device, during the inspiratory muscle fatigue protocol in COPD cases and the healthy control group.

CONDITIONS

Official Title

Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Stage 2-3 COPD according to ATS-ERS criteria
  • Using the same COPD medications for the last 4 weeks
  • For healthy participants: over 18 years old
  • For healthy participants: no diagnosed chronic disease
  • For healthy participants: not a smoker
Not Eligible

You will not qualify if you...

  • Severe comorbid diseases, unstable coronary artery disease, collagen vascular diseases
  • Requiring high-flow oxygen therapy (≥ 3-4 L/min)
  • Any vascular problems affecting lower extremity muscle oxygenation
  • Other respiratory diseases besides COPD
  • Acute COPD exacerbation in the last 4 weeks
  • Experiencing COPD exacerbations during the study
  • Fatty or scar tissue at measurement points affecting measurement quality
  • Participation in another clinical trial within the last 30 days that may affect study results

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Yedikule Chest Disease Hospital

Istanbul, Zeytinburnu, Turkey (Türkiye), 34200

Actively Recruiting

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Research Team

E

ESRA PEHLİVAN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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