Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT04067830

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

Led by Roswell Park Cancer Institute · Updated on 2025-09-05

220

Participants Needed

1

Research Sites

417 weeks

Total Duration

On this page

Sponsors

R

Roswell Park Cancer Institute

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This phase II trial studies how well respiratory muscle training before surgery works in preventing lung complications after surgery in patients with stage I-IIIB lung cancer. Patients with lung cancer who choose to undergo surgical resection often have complications after surgery such as pneumonia, unplanned intubations, difficulty breathing and reduced physical functioning, and increased medical costs and a reduced quality of life. Improving pre-surgical pulmonary health through respiratory muscle training may improve respiratory muscle strength, response to surgery, and quality of life after surgery in patients with lung cancer.

CONDITIONS

Official Title

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Documented stage I-IIIb lung cancer or undergoing surgery for diagnosis
  • Ability to speak, read, and comprehend English
  • Scheduled for video-assisted thoracic surgery or laparoscopic surgery for lung cancer removal
  • Patients may have had neoadjuvant chemoradiotherapy before surgery
  • Ability to follow written and verbal instructions
  • Provided written informed consent approved by ethics committee
Not Eligible

You will not qualify if you...

  • History of ischemic heart disease, congestive heart failure, or significant cardiac arrhythmias excluding surgery
  • Overall medical frailty or ECOG performance status greater than 2
  • Pregnant or nursing female participants
  • Unable or unwilling to follow study protocol
  • Any condition deemed unsuitable for participation by the investigator

AI-Screening

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Trial Site Locations

Total: 1 location

1

Roswell Park Cancer Institute

Buffalo, New York, United States, 14263

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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