Actively Recruiting
Respiratory Muscles and Work of Breathing in Children
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-04-03
550
Participants Needed
1
Research Sites
310 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
U
URC-CIC Paris Descartes Necker Cochin
Collaborating Sponsor
AI-Summary
What this Trial Is About
Respiratory muscle testing allows a quantitative assessment of inspiratory and expiratory muscles in children of any age with primary or secondary respiratory muscle impairment, in order to better understand the pathophysiology of respiratory impairment and guide therapeutic management. The use of an invasive technique (esogastric probe) makes it possible to specifically explore the diaphragm, the accessory inspiratory muscles and the expiratory muscles in order to detect dysfunction or paralysis of these muscles, and to estimate the work of breathing in order to better guide the respiratory management. The primary objective of the study is to evaluate the respiratory effort in children with primary or secondary impairment of the respiratory muscles during spontaneous breathing or during mechanical ventilation.
CONDITIONS
Official Title
Respiratory Muscles and Work of Breathing in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged less than 18 years old with primary or secondary impairment of respiratory muscles and followed at Necker Hospital
- Patients under spontaneous breathing or noninvasive or invasive mechanical ventilation
- Written informed consent
You will not qualify if you...
- No social insurance
- Significant psychomotor retardation
- Absence of cooperation
- Significant agitation
- Hemodynamic instability
- Acute condition or temporary drug treatments that may interfere with the results of the respiratory muscle explorations
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hôpital Necker-Enfants Malades
Paris, France, 75015
Actively Recruiting
Research Team
B
Brigitte FAUROUX, MD, PhD
CONTACT
H
Hélène MOREL
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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