Actively Recruiting
Respiratory Virus Infections in Acute Heart Failure
Led by Minjae Yoon · Updated on 2026-03-11
360
Participants Needed
3
Research Sites
194 weeks
Total Duration
On this page
Sponsors
M
Minjae Yoon
Lead Sponsor
S
Samsung Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
Patients admitted to the cardiology department with acute heart failure who have a nasopharyngeal respiratory virus PCR test performed within 72 hours of admission will be enrolled in the study cohort. The detection rate of respiratory viruses including influenza virus, RSV, and coronavirus will be analysed. The investigators will also look for seasonal changes in the frequency of respiratory viruses and differences in the clinical presentation of heart failure based on respiratory virus infection.
CONDITIONS
Official Title
Respiratory Virus Infections in Acute Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult aged 19 years or older admitted to the cardiology department with acute heart failure
- NT-proBNP >300 pg/mL
- Clinician judgement of possible respiratory viral infection (fever >38 degrees or cough, respiratory symptoms such as sputum or consolidation on x-ray or CRP >5 mg/dL)
- Patients who have a nasopharyngeal swab for respiratory virus PCR test performed within 72 hours of admission for any of the 3 reasons
You will not qualify if you...
- Patients with a clear other cause of acute heart failure (ex. ACS, bradycardia requiring a pacemaker, uncontrolled tachycardia, uncontrolled severe hypertension (SBP >180mmHg or DBP >110mmHg), haemoglobin <7g/dL or AHF precipitated by medication non-adherence)
- If the cause of pulmonary oedema is prominently attributed to exacerbation of CKD
- If there is a clear other source of infection that can explain the fever
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea, 13620
Actively Recruiting
2
Samsung medical center
Seoul, South Korea
Actively Recruiting
3
Seoul ST. Mary's Hospital
Seoul, South Korea
Actively Recruiting
Research Team
M
Minjae Yoon, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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