Actively Recruiting

Age: 25Years +
FEMALE
NCT03396341

Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-02-09

400

Participants Needed

7

Research Sites

469 weeks

Total Duration

On this page

Sponsors

M

Memorial Sloan Kettering Cancer Center

Lead Sponsor

P

Phenogen Sciences

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to describe how women with BRCA1/2 mutations react to genetic risk modifier testing, and to examine how they make decisions about their healthcare.

CONDITIONS

Official Title

Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations

Who Can Participate

Age: 25Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patient, age 25 years or older
  • Clinically confirmed BRCA1 or BRCA2 deleterious mutation from full sequence or targeted genetic testing
  • No personal history of breast cancer
  • Fluent in English to complete surveys
Not Eligible

You will not qualify if you...

  • Previous receipt of any prophylactic mastectomy
  • Major psychiatric illness or cognitive impairment that would prevent study participation
  • Inability to comply with study procedures as determined by study staff

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 7 locations

1

Dana Farber Cancer Institute (Data Collection Only)

Boston, Massachusetts, United States, 02115

Actively Recruiting

2

Memorial Sloan-Kettering at Basking Ridge

Basking Ridge, New Jersey, United States, 07920

Actively Recruiting

3

Memorial Sloan Kettering Commack

Commack, New York, United States, 11725

Actively Recruiting

4

Memorial Sloan Kettering Westchester

Harrison, New York, United States, 10604

Actively Recruiting

5

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Actively Recruiting

6

Memorial Sloan Kettering Nassau

Uniondale, New York, United States, 11553

Actively Recruiting

7

Abramson Cancer Center at University of Pennsylvania Medical Center (Data Collection Only)

Philadelphia, Pennsylvania, United States, 19104-4283

Actively Recruiting

Loading map...

Research Team

J

Jada Hamilton, PhD, MPH

CONTACT

M

Mark Robson, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations | DecenTrialz