Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT07252011

Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)

Led by University of Pittsburgh · Updated on 2026-03-03

60

Participants Needed

1

Research Sites

165 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Study to examine the extent to which neurophysiological states recorded for a specific person on one day can be induced on a subsequent day

CONDITIONS

Official Title

Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults age 18-65
  • Have periods of good and bad moods each lasting at least 2 days
Not Eligible

You will not qualify if you...

  • Refusal or inability to provide informed consent
  • Currently in frank psychotic episodes or unable to stay off psychoactive substances during assessments
  • Bipolar I disorder with current or apparent manic state at baseline
  • Inability to complete questionnaires written in English
  • Chronic pain that could be worsened by electrical stimulation
  • Difficulties in corrected vision or hearing preventing processing of experimental stimuli
  • North American Adult Reading Test (NAART) equivalent full scale IQ less than 85
  • History of convulsive disorder
  • Neurologic disorder or medication therapy known to lower seizure threshold
  • Deemed not a good fit for the study for other behavioral or safety reasons
  • Heart condition
  • Current severe DSM-V alcohol or substance use disorder (except nicotine or caffeine)
  • Metal implants near stimulated areas or electrical implants like pacemakers or vagus nerve stimulators
  • Any metal implant or subcutaneous metal in the face or head

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

G

Greg Siegle, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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