RESTORE Study to Reduce Future Fragility Fractures and Improve Outcomes in Adults 50 and Older

What this Trial Is About

Researchers are evaluating two approaches to improve care for people aged 50 and older who have recently had a fragility fracture, a break in bones caused by osteoporosis. The study, called RESTORE, compares an Augmented-Fracture Liaison Service where patient navigators help guide patients to bone health specialists, to Enhanced Usual Care, which provides education materials and encourages follow-up with primary care doctors. The study also examines how factors like age, race, ethnicity, sex, poverty, and geographic region affect the success of these strategies. Participants are randomly assigned to one of two groups. One group receives mailed education materials and encouragement to see their primary care provider. The other group receives the same materials plus contact from a patient navigator who assists in scheduling and attending appointments with a bone health clinician. This study uses a single-blind design and follows participants for at least 24 months after randomization. During the study, participants will be monitored for any new fractures occurring within 24 months. Researchers will collect information on participants health outcomes and adherence to recommended care. The trial requires participants to have had a recent fragility fracture and a regular primary care provider and to remain near the study site for follow-up. Safety and progress will be observed throughout the study, which is led by the University of Alabama at Birmingham.

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE