Actively Recruiting
Restricted Versus Liberal Fluid Intake for Prevention of Bronchopulmonary Dysplasia
Led by University Children's Hospital Basel · Updated on 2026-05-08
750
Participants Needed
9
Research Sites
229 weeks
Total Duration
On this page
Sponsors
U
University Children's Hospital Basel
Lead Sponsor
S
Swiss Neonatal Network
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this study is to determine whether restricted fluid intake (135 ±5 mL/kg/day) compared to liberal fluid intake (165 ±5 mL/kg/day) from day 8 of life reduces the incidence of bronchopulmonary dysplasia (BPD) at 36 weeks postmenstrual age or prior death in preterm infants born \<30 weeks gestational age.
CONDITIONS
Official Title
Restricted Versus Liberal Fluid Intake for Prevention of Bronchopulmonary Dysplasia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hospitalised preterm infants born before 30 weeks 0 days gestation
- Signed informed consent for further research use of health-related data
You will not qualify if you...
- congenital malformations
- diseases likely to affect life expectancy, lung function, fluid strategy, or neurodevelopment
- renal disease requiring fluid management outside the clinical standard of care
- congenital heart disease not including patent ductus arteriosus (PDA)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 9 locations
1
Kantonsspital Aarau AG, Klinik für Kinder u. Jugendliche
Aarau, Switzerland, 5001
Actively Recruiting
2
University Children's Hospital Basel (UKBB)
Basel, Switzerland, 4056
Actively Recruiting
3
Inselspital Bern, Kinderklinik
Bern, Switzerland, 3010
Actively Recruiting
4
Kantonsspital Graubünden, Departement Kinder- und Jugendmedizin
Chur, Switzerland, 7000
Actively Recruiting
5
Hôpitaux universitaires de Genève (HUG), Unité de Néonatologie
Geneva, Switzerland, 1205
Actively Recruiting
6
Centre hospitalier universitaire vaudois (CHUV) - Service de néonatologie
Lausanne, Switzerland, 1011
Actively Recruiting
7
Luzerner Kantonsspital, Kinderspital
Lucerne, Switzerland, 6000
Actively Recruiting
8
Ostschweizer Kinderspital & Neonatologie und Frauenklinik KSSG, Perinatalzentrum St. Gallen
Sankt Gallen, Switzerland, 9006
Actively Recruiting
9
UniversitätsSpital Zürich, Klinik für Neonatologie
Zurich, Switzerland, 8091
Actively Recruiting
Research Team
A
Anne Carrer
CONTACT
M
Michel Schrutt
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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