Actively Recruiting
Comparing Restrictive and Liberal Fluid Use During Elective Cesarean Section Under Spinal Anesthesia and Their Effects on Nausea, Vomiting, and Recovery
Led by Nigde Omer Halisdemir University · Updated on 2026-03-10
160
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying the effects of different fluid administration strategies during elective cesarean sections performed under spinal anesthesia. This trial compares restrictive 3 mLkgh and liberal >3 mLkgh crystalloid fluid approaches to understand their impact on maternal outcomes such as postoperative nausea and vomiting PONV, postdural puncture headache PDPH, gastrointestinal recovery, and intraoperative blood pressure stability. Participants will be randomly assigned to receive either a restrictive or liberal fluid infusion during surgery, with all other anesthetic procedures standardized. Hypotension during surgery will be managed using a predefined rescue protocol including medications like ephedrine and additional fluid boluses as needed. The study is designed as a prospective, single-center, randomized controlled trial. Throughout the study, researchers will monitor the incidence of PONV within 24 hours after surgery as the primary outcome. Secondary outcomes include PDPH severity, time to first flatus indicating bowel recovery, frequency of hypotension during surgery, and vasopressor use. Data on fluid administration and hemodynamic parameters will be collected to evaluate the effects of the fluid strategies on postoperative recovery and maternal health.
CONDITIONS
Brief Title
Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section
Research Team
P
Pınar Erdoğan, Assoc. Prof.
S
Seval Kılbasanlı, MD
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