+1 877 705 1914• 24 / 7
HIPAA Compliant
ISO 27001 Certified

Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
ID07440667

Comparing Restrictive and Liberal Fluid Use During Elective Cesarean Section Under Spinal Anesthesia and Their Effects on Nausea, Vomiting, and Recovery

Led by Nigde Omer Halisdemir University · Updated on 2026-03-10

160

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are studying the effects of different fluid administration strategies during elective cesarean sections performed under spinal anesthesia. This trial compares restrictive 3 mLkgh and liberal >3 mLkgh crystalloid fluid approaches to understand their impact on maternal outcomes such as postoperative nausea and vomiting PONV, postdural puncture headache PDPH, gastrointestinal recovery, and intraoperative blood pressure stability. Participants will be randomly assigned to receive either a restrictive or liberal fluid infusion during surgery, with all other anesthetic procedures standardized. Hypotension during surgery will be managed using a predefined rescue protocol including medications like ephedrine and additional fluid boluses as needed. The study is designed as a prospective, single-center, randomized controlled trial. Throughout the study, researchers will monitor the incidence of PONV within 24 hours after surgery as the primary outcome. Secondary outcomes include PDPH severity, time to first flatus indicating bowel recovery, frequency of hypotension during surgery, and vasopressor use. Data on fluid administration and hemodynamic parameters will be collected to evaluate the effects of the fluid strategies on postoperative recovery and maternal health.

CONDITIONS

Brief Title

Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section

Research Team

P

Pınar Erdoğan, Assoc. Prof.

S

Seval Kılbasanlı, MD

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here