Actively Recruiting

Phase Not Applicable
Age: 45Years +
All Genders
NCT05624398

Results of Patients With Glaucoma Undergoing Minimally Invasive Glaucoma Surgery in Conjunction With Cataract Surgery

Led by Vold Vision P.L.L.C · Updated on 2024-08-13

25

Participants Needed

1

Research Sites

125 weeks

Total Duration

On this page

Sponsors

V

Vold Vision P.L.L.C

Lead Sponsor

A

Alcon Research

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is designed to determine how well patients with glaucoma can see following cataract surgery with a special type of lens called an extended-depth-of-focus (EDOF) lens. This lens is intended to reduced the patients need for glasses following cataract surgery. Patients will also undergo a minimally invasive type of glaucoma surgery using a special type of stent to reduce eye pressure, with the goal of better glaucoma control and the reduction in the need for medications to control eye pressure.

CONDITIONS

Official Title

Results of Patients With Glaucoma Undergoing Minimally Invasive Glaucoma Surgery in Conjunction With Cataract Surgery

Who Can Participate

Age: 45Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female subjects 45 years of age or older
  • Presence of visually significant age-related cataract in both eyes
  • Diagnosis of mild open-angle glaucoma with visual field mean deviation not worse than -6.00 dB and/or nerve abnormalities consistent with glaucoma
  • Medicated intraocular pressure at or below 25 mmHg on 1 to 3 hypotensive medications
  • Glaucoma judged as stable by investigator with stable visual field and nerve fiber layer for at least 1 year and stable intraocular pressure on current medication for at least 3 months
  • Shaffer grade of 3 or higher in all angle quadrants
  • Potential for best corrected visual acuity at distance of at least 0.1 logMAR (20/25) postoperatively
  • Able and willing to comply with follow-up visits
  • Understands and signs informed consent
  • Both eyes to undergo surgery within 21 days of each other
Not Eligible

You will not qualify if you...

  • Previous incisional glaucoma surgery or cilio-ablative surgery
  • Prior laser trabeculoplasty within 90 days of surgery
  • Diagnosis of pseudoexfoliative, angle closure, uveitic, congenital, traumatic, angle recession, or neovascular glaucoma
  • Moderate glaucoma with visual field mean deviation between -6.00 dB and -12.00 dB
  • Severe or progressive glaucoma defined by visual field mean deviation worse than -12.00 dB, consistent worsening of visual field, progressive nerve fiber layer thinning, uncontrolled intraocular pressure on maximum medications, history of poor pressure control, severe optic nerve rim notching, or expectation for future incisional glaucoma surgery
  • Ocular or medical conditions increasing risk of complications or significant vision loss during study
  • Ocular pathologies impacting visual acuity postoperatively such as significant ocular surface disease, corneal scarring, blepharitis, epiretinal membrane, macular degeneration, or history of significant ocular trauma
  • Pregnant or breastfeeding women
  • Prior refractive surgery such as LASIK, RK, or PRK
  • Significant complications during surgery or related to Hydrus Microstent resulting in study exit

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Vold Vision P.L.L.C.

Fayetteville, Arkansas, United States, 72764

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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