Actively Recruiting

Age: 0 - 18Years
All Genders
ID05373498

Pediatric Resuscitation Outcome in Children With Heart Disease A Registry Study on Cardiac Arrest and Neurological Outcomes

Led by Leipzig Heart Science gGmbH · Updated on 2025-01-16

400

Participants Needed

3

Research Sites

541 weeks

Total Duration

On this page

Sponsors

L

Leipzig Heart Science gGmbH

Lead Sponsor

H

Heart Center Leipzig - University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Children with congenital heart defects have a much higher chance of experiencing a cardiac arrest and needing resuscitation than healthy children or those with other diseases, especially after heart surgery. The exact number of such resuscitations and their outcomes are not well known. This study aims to collect detailed information on cardiac arrests in children with heart disease and to examine survival rates and neurological outcomes. This research is an observational registry collecting data prospectively from multiple centers in Germany. It includes children aged 0 to 18 years with heart conditions who experience a cardiac arrest requiring at least two minutes of chest compressions in hospital or upon arrival. The study gathers information on patient demographics, resuscitation details, post-resuscitation care, and follow-up neurological assessments using a web-based system. Participants will be followed until hospital discharge or death, with survival being the primary outcome measured up to two months. Researchers will also study morbidity, especially neurological impacts, and analyze how patient and treatment factors relate to outcomes. This registry aims to improve understanding and care for children with heart disease who suffer cardiac arrest by providing comprehensive data on mortality and neurological health after resuscitation.

CONDITIONS

Official Title

Resuscitation Registry in CHD

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children under 18 years with congenital heart defects, congenital heart arrhythmias, familial cardiomyopathies, or inflammatory heart diseases
  • Cardiac arrest requiring chest compressions for at least 2 minutes in hospital or upon hospital arrival
  • Informed consent provided by parents or legal representatives
Not Eligible

You will not qualify if you...

  • Lack of or withdrawal of informed consent by parents or legal representatives
  • Presence of a do-not-resuscitate (DNR) order

AI-Screening

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Trial Site Locations

Total: 3 locations

1

Herzzentrum Leipzig

Leipzig, Saxony, Germany, 04289

Actively Recruiting

2

Deutsches Herzzentrum Berlin

Berlin, Germany, 13353

Not Yet Recruiting

3

Universitätsklinikum Bonn (AöR)

Bonn, Germany, 53127

Not Yet Recruiting

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Research Team

F

Franziska Markel, Dr. med.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Paediatric Resuscitation Outcome in Children with Heart Disease (ProCHD): protocol of a Germany-wide multicentre, prospective open registry.

Franziska Markel, Peter Kramer, Jeanine Anand...

https://pubmed.ncbi.nlm.nih.gov/41506771