Paediatric Resuscitation Outcome in Children with Heart Disease (ProCHD): protocol of a Germany-wide multicentre, prospective open registry.
Franziska Markel, Peter Kramer, Jeanine Anand...
https://pubmed.ncbi.nlm.nih.gov/41506771Actively Recruiting
Led by Leipzig Heart Science gGmbH · Updated on 2025-01-16
400
Participants Needed
3
Research Sites
541 weeks
Total Duration
L
Leipzig Heart Science gGmbH
Lead Sponsor
H
Heart Center Leipzig - University Hospital
Collaborating Sponsor
Children with congenital heart defects have a much higher chance of experiencing a cardiac arrest and needing resuscitation than healthy children or those with other diseases, especially after heart surgery. The exact number of such resuscitations and their outcomes are not well known. This study aims to collect detailed information on cardiac arrests in children with heart disease and to examine survival rates and neurological outcomes. This research is an observational registry collecting data prospectively from multiple centers in Germany. It includes children aged 0 to 18 years with heart conditions who experience a cardiac arrest requiring at least two minutes of chest compressions in hospital or upon arrival. The study gathers information on patient demographics, resuscitation details, post-resuscitation care, and follow-up neurological assessments using a web-based system. Participants will be followed until hospital discharge or death, with survival being the primary outcome measured up to two months. Researchers will also study morbidity, especially neurological impacts, and analyze how patient and treatment factors relate to outcomes. This registry aims to improve understanding and care for children with heart disease who suffer cardiac arrest by providing comprehensive data on mortality and neurological health after resuscitation.
CONDITIONS
Resuscitation Registry in CHD
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Total: 3 locations
1
Herzzentrum Leipzig
Leipzig, Saxony, Germany, 04289
Actively Recruiting
2
Deutsches Herzzentrum Berlin
Berlin, Germany, 13353
Not Yet Recruiting
3
Universitätsklinikum Bonn (AöR)
Bonn, Germany, 53127
Not Yet Recruiting
F
Franziska Markel, Dr. med.
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Franziska Markel, Peter Kramer, Jeanine Anand...
https://pubmed.ncbi.nlm.nih.gov/41506771