Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06369766

REtinal Markers In Neuroinflammatory Diseases ("REMIND")

Led by University Hospital, Basel, Switzerland · Updated on 2025-05-23

500

Participants Needed

1

Research Sites

261 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Basel, Switzerland

Lead Sponsor

U

University of Basel

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study, including patients with Multiple Sclerosis, patients with other neuroinflammatory diseases and healthy controls, is to determine the predictive value of retinal markers in predicting disease progression. Participants complete a questionnaire and undergo various non-invasive retinal routine clinical examinations.

CONDITIONS

Official Title

REtinal Markers In Neuroinflammatory Diseases ("REMIND")

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years old
  • Diagnosis of Multiple Sclerosis according to the 2017 McDonald Criteria for MS patients
  • Diagnosis of Neuromyelitis optica spectrum disorder, Myelin oligodendrocyte glycoprotein antibody disease, or other neuroinflammatory disorders for non-MS patients
Not Eligible

You will not qualify if you...

  • Inability to undergo Optical Coherence Tomography (OCT) or retinal vessel imaging (e.g. severe nystagmus preventing eye fixation)
  • Presence of ocular diseases interfering with OCT or retinal vessel analysis validity (e.g., cataracts, glaucoma, history of refractive defects >6 diopters)
  • Pregnancy or lactation
  • For healthy controls: history of other significant neurological conditions affecting assessment or symptom interpretation (e.g., stroke, acute disseminated encephalomyelitis, chronic inflammatory demyelinating disease, polyneuropathy)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Basel, Department of Neurology

Basel, Switzerland, 4031

Actively Recruiting

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Research Team

A

Athina Papadopoulou, PD Dr. med.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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