Actively Recruiting
Retrolaminar Analgesia for LuMbar Surgery
Led by Universidad de los Andes, Chile · Updated on 2026-04-13
50
Participants Needed
1
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized controlled trial evaluates the effectiveness of ultrasound-guided retrolaminar nerve block in addition to standard multimodal analgesia for postoperative pain management in patients undergoing lumbar spine surgery. Fifty patients will be randomly assigned to receive either the retrolaminar block combined with standard pain management or standard pain management alone. The primary outcome is total opioid consumption in the first 24 hours after surgery. Secondary outcomes include pain intensity at multiple time points, time to first rescue analgesia, duration of sensory block, incidence of postoperative nausea and vomiting, length of hospital stay, patient satisfaction, and chronic pain development at 3 and 6 months follow-up.
CONDITIONS
Official Title
Retrolaminar Analgesia for LuMbar Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients aged 18-80 years
- Scheduled for elective lumbar spine surgery with instrumentation
- American Society of Anesthesiologists (ASA) physical status I-III
- Willing and able to provide written informed consent
- Able to use patient-controlled analgesia (PCA) device
You will not qualify if you...
- Refusal to participate in the study
- Known allergy to local anesthetics (bupivacaine, levobupivacaine, lidocaine) or any study medication
- Contraindication to regional anesthesia such as infection at injection site or coagulopathy
- Chronic opioid use daily for more than 3 months prior to surgery
- Severe psychiatric disorder preventing informed consent
- Emergency surgery
- Diabetes mellitus with preoperative glucose over 180 mg/dl
- Pregnancy or breastfeeding
- Body mass index (BMI) over 40 kg/m²
- Reoperation or revision of the same level of previous spinal surgery
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Clínica Universidad de los Andes, Chile
Santiago, Santiago Metropolitan, Chile, 171571
Actively Recruiting
Research Team
R
Roberto Coloma, MD
CONTACT
N
Nicolás Valls, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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