Retrospective Analysis of Chinese Adults With Gastroesophageal Reflux Disease Using a National Clinical Database Characterizing Patient Profiles, Treatments, and Long-Term Outcomes

What this Trial Is About

This observational study analyzes data from a large prospective clinical registry to understand the characteristics and treatment outcomes of Chinese adults diagnosed with gastroesophageal reflux disease GERD. It aims to describe patient demographics, clinical features, psychological status, and treatment approaches while assessing improvements in GERD symptoms and psychological well-being after treatment. Researchers collected retrospective data on about 5,000 GERD patients treated at Beijing Friendship Hospital, including baseline information, diagnostic findings, psychological assessments before treatment, surgical complications, and long-term follow-up outcomes. The treatment types studied include pharmacological therapy and anti-reflux surgery, with data spanning up to 10 years post-treatment. Participants clinical records were reviewed to measure various outcomes such as symptom improvement, esophagitis severity, reflux indicators, and psychological health scores before and after treatment. The study also monitors surgical details, medication regimens, and postoperative complications. This comprehensive analysis provides insights to help guide personalized treatment decisions for GERD patients in China.

A Retrospective Analysis of Patients With Gastroesophageal Reflux Disease Based on a Prospective Clinical Dataset