Actively Recruiting
Retrospective Evaluation of Patients Diagnosed With Pre- and Postnatal Urinary Tract Dilatation Outcomes and Long-Term Follow-Up in Children
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-08
600
Participants Needed
1
Research Sites
287 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Urinary tract dilatation is a common congenital condition in children, often detected early due to advances in imaging techniques, especially prenatal ultrasound screening. This condition is found in about 1-2% of pregnancies and is more common in males. Early diagnosis aims to monitor urinary tract abnormalities and prevent complications that could lead to kidney damage. However, detecting mild abnormalities that do not require treatment can cause unnecessary worry and medical tests for families. Postnatal diagnoses occur through childhood screenings, follow-ups after urinary infections or abdominal pain, or monitoring during hospital stays for other reasons. This research retrospectively reviews patients diagnosed with urinary tract dilatation either before or after birth. It evaluates diagnostic approaches, disease progression, and different outcomes over time. The study focuses on identifying which cases need close monitoring and additional tests, such as specialized imaging techniques, and determining the best timing for these examinations. It also compares the risks and benefits of prenatal versus postnatal screening to assess if postnatal screening is necessary when prenatal diagnosis is already done. Participants in this study are children diagnosed with urinary tract dilatation who have undergone at least two ultrasounds postnatally. Researchers review ultrasound measurements, check for kidney and bladder abnormalities, and assess kidney size and tissue characteristics. The study analyzes these data to understand the condition's progression and outcomes and to improve management strategies. Data collection covers a long-term follow-up period, allowing evaluation of the condition from diagnosis through ongoing monitoring.
CONDITIONS
Official Title
Retrospective Evaluation of a Cohort of Patients Diagnosed With Pre- and Postnatal Urinary Dilatation: Outcome and Long-term Follow-up
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pediatric patients referred between January 1, 2000, and August 31, 2021, with prenatal or postnatal diagnosis of urinary tract dilatation
- Urinary tract dilatation confirmed by at least one postnatal ultrasound with measurements
- At least one additional postnatal ultrasound performed during follow-up
You will not qualify if you...
- Missing important clinical data, especially incomplete ultrasound reports from at least two follow-up ultrasounds
- Urinary tract dilatation associated with confirmed kidney stones (renal lithiasis)
AI-Screening
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Trial Site Locations
Total: 1 location
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy, 40138
Actively Recruiting
Research Team
C
Claudio La Scola, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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