Actively Recruiting
Retrospective Evaluation of Minimally-Invasive Surgical Strategies in Ovarian Neoplasms (REMISSION Study)
Led by Jvan Casarin, MD PhD · Updated on 2025-03-17
1500
Participants Needed
1
Research Sites
176 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study aims to evaluate the outcomes of patients with early-stage epithelial ovarian cancer who are treated with minimally invasive surgery (such as laparoscopic or robotic surgery). Specifically, the study will look at: 1. Post-Surgery Complications * What is the rate of complications within 30 days after surgery? * How often do patients require readmission to the hospital, re-operation, or conversion to open surgery? 2. Cancer Outcomes * What is the rate of cancer upstaging (when the cancer spreads to a more advanced stage during surgery for example because of an intra-operative ovarian cyst rupture)? * What are the overall survival and disease-free survival rates for patients treated with minimally invasive surgery? Researchers will compare two groups of patients: Group 1: Patients with early-stage ovarian cancer treated with minimally invasive surgery. Group 2: Patients with early-stage ovarian cancer treated with open surgery. The goal is to see if there are any differences in post-surgery complications, recovery, and cancer outcomes between the two groups. Fertility-Sparing Treatment: The study will also compare patients who are undergoing fertility-sparing treatments for early-stage ovarian cancer. Two subgroups will be looked at: * Patients receiving fertility-sparing surgery through a minimally invasive procedure. * Patients receiving fertility-sparing surgery through an open surgery. The same outcomes (complications, survival, etc.) will be assessed and compared between these two groups as well.
CONDITIONS
Official Title
Retrospective Evaluation of Minimally-Invasive Surgical Strategies in Ovarian Neoplasms (REMISSION Study)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with apparent early-stage epithelial ovarian cancer at preoperative evaluation
- Patients who underwent surgery between January 2014 and December 2023
- Patients who underwent open or minimally invasive surgical staging (Laparoscopic or Robotic-assisted approach) or restaging procedure
- Patients with final pathology report of Epithelial Ovarian Cancer
You will not qualify if you...
- Patients who have not performed a complete surgical staging
- Patients who underwent neoadjuvant chemotherapy
- Patients with invasive synchronous tumor
- Patients with no informed consent
- Patients with ASA class score of 4 or 5
AI-Screening
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Trial Site Locations
Total: 1 location
1
Ospedale Filippo del Ponte
Varese, Varese, Italy, 21100
Actively Recruiting
Research Team
J
Jvan Casarin, Medical Doctor
CONTACT
A
Anna Giudici, Medical Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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