Actively Recruiting

Age: 15Years - 39Years
FEMALE
NCT07015476

Retrospective Observational Evaluation of the Bone Mineral Density Outcome in Young Women With Amenorrhea

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-06-11

180

Participants Needed

1

Research Sites

311 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims to evaluate the outcomes of different estrogen therapy regimens in patients with amenorrhea who face prolonged periods of hypoestrogenism. The primary objective is to compare the outcomes on bone mass of different therapeutic regimens and identify more favorable. For this purpose, densitometry parameters such as BMD, T-score and Z-score at the level of the lumbar spine, femur and entire skeleton will be considered, comparing a bone densitometry (DXA technique, Dual X-ray Absorptiometry) Baseline with one carried out after at least one year of therapy. The secondary objective of the study is to assess other systemic/metabolic implications of the different therapies.

CONDITIONS

Official Title

Retrospective Observational Evaluation of the Bone Mineral Density Outcome in Young Women With Amenorrhea

Who Can Participate

Age: 15Years - 39Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged between 15 and 39 years with amenorrhea lasting over 6 months who visited the Gynecology and Human Reproduction center between 2011 and 2020
  • Patients who were at least 18 years old at the time of surgery
  • Patients who have provided informed consent
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

IRCCS Azienda Ospedaliero -Univeristaria di Bologna

Bologna, Italy, 40138

Actively Recruiting

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Research Team

M

Maria C Meriggiola, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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Retrospective Observational Evaluation of the Bone Mineral Density Outcome in Young Women With Amenorrhea | DecenTrialz