Actively Recruiting

Age: 5Years - 85Years
All Genders
NCT05193162

Retrospective Study on Microbial Diversity in Paraffin Tissue of Pancreatic Diseases

Led by Ruijin Hospital · Updated on 2023-06-15

800

Participants Needed

1

Research Sites

391 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The great harm of pancreatic diseases and the unknown etiology and pathogenesis make it difficult to intervene in most early cases in time. Previous studies by scholars and applicants at home and abroad have shown that the microflora in pancreatic tissue is closely related to chronic pancreatitis and pancreatic cancer. However, the research on the mechanism of microbial diversity in pancreatic tissue and the occurrence and development of various pancreatic diseases has not been reported. Based on the previous research, this subject continues to take various pancreatic diseases as the research object based on the database of pancreatic center and pathology department of Ruijin Hospital Affiliated to Medical College of Shanghai Jiaotong University, To explore the characteristics of microbial flora in pancreas in different pancreatic diseases and its mechanism of influence on disease microenvironment. Select specific microbial flora or targets in the pancreas for various pancreatic diseases, so as to provide new theoretical basis and practical guidance for the early diagnosis and treatment of pancreatic diseases.

CONDITIONS

Official Title

Retrospective Study on Microbial Diversity in Paraffin Tissue of Pancreatic Diseases

Who Can Participate

Age: 5Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 5 years or older and 85 years or younger
  • Patient must have undergone routine surgery with postoperative pathology confirming pancreatic cancer or other pancreatic diseases
  • No use of antibiotics or yogurt containing probiotics for three months before surgery
  • No serious damage to heart, liver, or kidney function
Not Eligible

You will not qualify if you...

  • Use of antibiotics or yogurt containing probiotics within three months
  • Evidence of sensory or motor neuropathy
  • Diagnosed cardiovascular disease, severe associated disease, or active infection including HIV
  • History of other cancers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ruijin Hospital

Shanghai, China, 200025

Actively Recruiting

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Research Team

W

Wei Wang, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

9

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