Actively Recruiting
Retrospective Study on Ventilator Weaning Outcomes in Patients With Acute Brain Injury
Led by Southeast University, China · Updated on 2026-04-01
1500
Participants Needed
1
Research Sites
425 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Invasive mechanical ventilation (IMV) is a life-saving supportive therapy for patients with acute brain injury, which accounted for nearly one-fifth of all mechanically ventilated patients in the intensive care unit (ICU). However, prolonged exposure to IMV is consistently associated with an increased risk of ventilator-related complications and adverse outcomes. Accordingly, alongside the initiation of IMV, timely and safe liberation from ventilator should be considered. Nevertheless, data detailing the weaning process and its associated outcomes in mechanically ventilated patients with ABI remain scarce. To address this gap, the investigators conducted an observational study aimed at characterizing the ventilator weaning process and outcomes in patients with ABI receiving IMV, using the modified WIND classification.
CONDITIONS
Official Title
Retrospective Study on Ventilator Weaning Outcomes in Patients With Acute Brain Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with ABI
- 18 years or older
- Underwent invasive mechanical ventilation for at least 24 hours
You will not qualify if you...
- Already tracheostomized
- Concurrent cervical spinal cord injury
- Pregnant or lactating
- Withdrawal of life-sustaining treatment within the first 24 hours of ICU admission
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Critical Care Medicine, Zhongda Hospital
Nanjing, Jiangsu, China, 210009
Actively Recruiting
Research Team
L
Ling Liu, PHD
CONTACT
R
Rui Zhang, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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