Actively Recruiting
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities
Led by Weill Medical College of Cornell University · Updated on 2025-10-01
600
Participants Needed
18
Research Sites
743 weeks
Total Duration
On this page
Sponsors
W
Weill Medical College of Cornell University
Lead Sponsor
P
Patient-Centered Outcomes Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a research study in minorities to compare the outcomes of two procedures that restore blood flow to the arteries of the heart. In one procedure the blockages are ballooned and then stented with a small wire mesh tube through a small incision in the wrist or the groin. The other procedure is an open-heart operation in which healthy blood vessels from inside the chest, leg, and/or forearm are used to "bypass" the blockages (like a detour). Outcomes will be measured by comparing survival and improvement in quality-of-life.
CONDITIONS
Official Title
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient must identify as a minority
- Patient is at least 18 years old
- Multivessel or left main coronary artery disease present with treatment equipoise between CABG and PCI as determined by the local Heart Team
- Ability to provide written informed consent and comply with follow-up including quality of life questionnaires
You will not qualify if you...
- ST-segment elevation myocardial infarction within 3 days
- Cardiogenic shock
- Prior PCI within 1 year or any prior CABG at any time
- Planned hybrid revascularization (PCI after CABG or CABG after PCI)
- Planned single vessel revascularization except isolated left main disease
- Need for other cardiac surgery or intervention now or anticipated within 3 years
- Pregnancy or intent to become pregnant within 1 year after randomization
- Unable to tolerate or comply with dual antiplatelet therapy for required durations
- Current participation in another investigational drug or device study not completed
- Life expectancy less than 3 years due to other non-cardiac conditions
- Any condition likely to interfere with study procedures or follow-up, such as mental disability, substance abuse, or anticipated relocation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 18 locations
1
Adventist Health Glendale
Glendale, California, United States, 91206
Actively Recruiting
2
Emory University
Atlanta, Georgia, United States, 30322
Actively Recruiting
3
Ascension St. Vincent Cardiovascular Research Institute
Carmel, Indiana, United States, 46290
Actively Recruiting
4
Baptist Health Lexington
Lexington, Kentucky, United States, 40503
Actively Recruiting
5
Baptist Health Louisville
Louisville, Kentucky, United States, 40207
Actively Recruiting
6
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
7
Englewood Hospital
Englewood, New Jersey, United States, 07631
Actively Recruiting
8
NewYork-Presbyterian Hospital - Queens
Flushing, New York, United States, 11355
Actively Recruiting
9
Icahn School of Medicine - Mount Sinai Morningside
New York, New York, United States, 10025
Actively Recruiting
10
Icahn School of Medicine - Mount Sinai Hospital
New York, New York, United States, 10029
Actively Recruiting
11
Columbia University Irving Medical Center/NewYork-Presbyterian Hospital
New York, New York, United States, 10032
Actively Recruiting
12
Weill Cornell Medicine/NewYork-Presbyterian Hospital
New York, New York, United States, 10065
Actively Recruiting
13
Westchester Medical Center
Valhalla, New York, United States, 10595
Actively Recruiting
14
Duke University
Durham, North Carolina, United States, 27710
Actively Recruiting
15
Ohio State University
Columbus, Ohio, United States, 43210
Actively Recruiting
16
Methodist Le Bonheur Healthcare
Memphis, Tennessee, United States, 38104
Actively Recruiting
17
Ascension Saint Thomas Hospital
Nashville, Tennessee, United States, 37205
Actively Recruiting
18
Baylor Scott and White
Dallas, Texas, United States, 75246
Actively Recruiting
Research Team
M
Mario Gaudino, MD, PhD, MSCE, FEBCTS, FACC
CONTACT
G
Gregg Stone, MD, FACC, MSCAI
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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