Actively Recruiting

Phase Not Applicable
Age: 19Years +
All Genders
NCT05828719

Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction

Led by Samsung Medical Center · Updated on 2025-03-14

900

Participants Needed

1

Research Sites

393 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Randomized trial to compare clinical outcomes between revascularization versus medical treatment alone in patients with ischemic cardiomyopathy and left ventricular dysfunction.

CONDITIONS

Official Title

Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 19 years old
  • Diagnosed with stage C heart failure and left ventricular ejection fraction below 40%
  • Significant coronary artery narrowing (diameter stenosis over 50%) with confirmed inducible myocardial ischemia
  • Coronary artery disease suitable for percutaneous coronary intervention (PCI)
  • Able to understand study risks, benefits, and alternatives and provide written informed consent
Not Eligible

You will not qualify if you...

  • Myocardial infarction within 4 weeks before randomization
  • Non-viable heart muscle shown by viability tests
  • Target lesions not suitable for PCI as decided by the operator
  • Need for left ventricular assist device or heart transplant at randomization
  • Intolerance to aspirin, clopidogrel, prasugrel, ticagrelor, heparin, or everolimus
  • Known anaphylaxis to contrast agents
  • Pregnancy or breastfeeding
  • Non-cardiac conditions limiting life expectancy to less than 2 years or causing protocol non-compliance
  • Unwillingness or inability to follow study procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Samsune Medical Center

Seoul, South Korea, 06351

Actively Recruiting

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Research Team

Y

Young Bin Song, MD, PhD

CONTACT

J

Joo Myung Lee, MD, MPH, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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