Actively Recruiting
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors
Led by Dana-Farber Cancer Institute · Updated on 2026-04-13
240
Participants Needed
6
Research Sites
202 weeks
Total Duration
On this page
Sponsors
D
Dana-Farber Cancer Institute
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to see whether a supportive intervention (REVITALIZE) reduces fatigue and its impact on daily life and activities for participants with ovarian cancer taking PARP inhibitors. The name of the study groups in this research study are: 1. REVITALIZE 2. Educational Materials
CONDITIONS
Official Title
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (age 63 18 years) with ovarian, fallopian tube, or primary peritoneal cancers who have completed primary therapy (surgery and chemotherapy)
- Treated with a PARP inhibitor as maintenance therapy for 63 2 months and plan to continue for at least 7 months
- English-speaking
- Mean fatigue severity level 63 4 on the first three items of the Fatigue Symptom Inventory
- ECOG performance status of 0-2
- Willing to use a wireless pill bottle for PARP inhibitor medication
You will not qualify if you...
- Untreated clinical or comorbid condition predating PARP inhibitor use that could explain fatigue
- Severe psychiatric conditions requiring more intensive treatment than the study can provide
- Cognitive conditions that prevent informed consent or study participation
- Inability to complete the first questionnaire within one week of consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
University of Colorado Cancer Center-Anschutz
Aurora, Colorado, United States, 80045
Actively Recruiting
2
University of Colorado Boulder
Boulder, Colorado, United States, 80309
Actively Recruiting
3
Massachusetts General Hospital-Cancer Center
Boston, Massachusetts, United States, 02114
Actively Recruiting
4
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02115
Actively Recruiting
5
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
6
Duke Cancer Center
Durham, North Carolina, United States, 27710
Actively Recruiting
Research Team
H
Hannah Park, BS
CONTACT
I
Irene Wang, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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