Clinical Outcomes and Quality of Life Measures After Surgical Resection and Radiofrequency Ablation of Benign Thyroid Nodules

What this Trial Is About

This research aims to evaluate and compare clinical outcomes and quality of life in adults with symptomatic benign multinodular goiter MNG, a common thyroid condition with nodules that may cause symptoms like swallowing or breathing difficulties. The study focuses on treatments for this condition, including surgical removal and radiofrequency ablation RFA, a newer technique that uses heat to shrink nodules. These approaches are being studied to understand their effects on symptoms and thyroid function over time. Participants in this observational study include those who undergo either surgical resection of thyroid nodules or radiofrequency ablation. The study collects data before and after treatment to assess outcomes. RFA is guided by ultrasound and is considered investigational in the United States but has been used internationally with positive results. Both treatments are compared to observe changes in nodule size, hormone levels, and symptoms. During the study, participants provide access to their medical information related to their thyroid nodules and treatment outcomes. Researchers will measure changes in nodule volume and thyroid stimulating hormone TSH levels at 6 and 12 months after treatment, along with quality of life assessed by the ThyPRO 39 survey at 12 months. The study helps gather long-term data on how these treatments affect thyroid nodules and patient well-being, with participation lasting at least a year.

RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study