Actively Recruiting

Age: 18Years +
All Genders
NCT05189821

RFA Treatment for Papillary Thyroid Microcarcinoma

Led by Columbia University · Updated on 2025-05-28

50

Participants Needed

1

Research Sites

313 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Thyroid surgery has always been the mainstay of treatment for thyroid cancer. Thyroid surgery carries a low risk of complications that include recurrent or superior laryngeal nerve injury leading to voice changes, hypoparathyroidism, hypothyroidism with need for thyroid hormone supplementation, and unsightly scarring. Although many patients with thyroid cancer find these risks acceptable, these risks are sometimes less acceptable to patients with benign disease. In an era when the medical field is treating thyroid diseases less aggressively, there is a pressing need to identify approaches to treat indolent malignant disease less invasively. The purpose of this observational study is to evaluate the efficacy and safety of Radiofrequency Ablation (RFA) for treatment of Papillary Thyroid Microcarcinoma (PTMC) in patients that have already agreed to RFA procedure based on treating physician recommendation. This is a data collection study in which we ask participants to give us access to information generated before and after RFA treatment of their condition. The RFA procedure uses image guidance to place an electrode through the skin into the target tumor. In RFA, high-frequency electrical currents are passed through an electrode, creating a small region of heat to treat the lesion.

CONDITIONS

Official Title

RFA Treatment for Papillary Thyroid Microcarcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients (≥ 18 years)
  • Biopsy proven papillary thyroid microcarcinoma (≥ 1.5cm in greatest diameter, PTMC)
  • Patients who refuse surgery or are not good surgical candidates
Not Eligible

You will not qualify if you...

  • Cardiac arrhythmia
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Columbia University

New York, New York, United States, 10032

Actively Recruiting

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Research Team

J

Jennifer H Kuo, MD MS

CONTACT

V

Vilma Rosario

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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RFA Treatment for Papillary Thyroid Microcarcinoma | DecenTrialz