Actively Recruiting
Rheological Functions of Erythrocyte in ESRD
Led by Chang Gung Memorial Hospital · Updated on 2025-03-11
40
Participants Needed
1
Research Sites
135 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
End-stage renal disease (ESRD) disrupts erythrocyte deformability due to osmotic imbalances, oxidative stress, and uremic toxins, leading to impaired microcirculation and oxygen transport. Dysregulation of ion channels, particularly the Gardos channel, exacerbates dehydration and eryptosis, further compromising vascular integrity. Given the critical role of erythrocyte flexibility in oxygen delivery, this study investigates its relationship with aerobic capacity in ESRD patients, highlighting potential mechanisms of microvascular dysfunction
CONDITIONS
Official Title
Rheological Functions of Erythrocyte in ESRD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Receiving hemodialysis and medication for at least 6 weeks
- Kt/V score greater than 1.2
- Age 20 years or older
You will not qualify if you...
- Under 20 years old
- Hyperkalemia within the last 3 months
- Having orthopedic or muscular diseases
- Having other medical, psychological, or physiological diseases
- Pregnancy
- Any other exercise contraindications
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Chang Gung University
Taoyuan, Taiwan, 333
Actively Recruiting
Research Team
J
Jong-Shyan Wang, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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