Actively Recruiting
Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic Rhinosinusitis
Led by Italian Academy of Rhinology · Updated on 2024-07-19
5000
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
Sponsors
I
Italian Academy of Rhinology
Lead Sponsor
A
Accademia Italiana di Citologia Nasale
Collaborating Sponsor
AI-Summary
What this Trial Is About
This observatory aims to collect, as widely as possible, the Italian cases of patients with uncontrolled CRS. Patient will be enrolled by the centers of the Italian Network of Rhinosinusitis (Rhinosinusitis Italian Network: RINET), and they will be treated using a multidisciplinary team approach (allergists, otolaryngologists and pneumologists) in a real-world clinical set-up. This real-life chronic rhinosinusitis registry aims at longitudinal data collection from patients attending specialist care centres across Italy.
CONDITIONS
Official Title
Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic Rhinosinusitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants with confirmed bilateral Chronic Rhinosinusitis diagnosis
- Patients previously treated with nasal sinus surgery must have at least three of these criteria
- Patients never treated with nasal sinus surgery must have at least four of these criteria
- Evidence of type 2 inflammation shown by blood or tissue eosinophils, nasal cytology, or high serum IgE
- At least two short courses or long-term systemic corticosteroid therapy for Chronic Rhinosinusitis
- Significant quality of life worsening (SNOT-22 score of 40 or higher and/or symptom severity score of 5 or higher)
- Loss of smell with a severity score of 7 or higher
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Personalized Medicine, Asthma and Allergy - IRCCS Humanitas Research Hospital
Rozzano, MIlan, Italy, 20089
Actively Recruiting
Research Team
E
Enrico Marco Heffler, MD, PhD
CONTACT
C
Concetta Sirena, Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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