Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
Healthy Volunteers
ID06856538

Analgesic Efficacy of Ultrasound-Guided Rhomboid Intercostal Sub Serratus Plane Block Versus Serratus Anterior Plane Block With General Anesthesia in Thoracotomy

Led by Yasser S Mostafa, MD · Updated on 2025-03-06

40

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to compare the pain relief effects of two ultrasound-guided nerve block techniques, the rhomboid intercostal sub-serratus plane (RISS) block and the serratus anterior plane block (SAPB), in patients undergoing thoracotomy surgery. Thoracotomy is known for causing severe postoperative pain that affects recovery and breathing. The study focuses on evaluating which of these regional anesthesia methods provides better pain control and reduces opioid use after surgery. Participants will receive either the RISS block or the SAPB under ultrasound guidance during their thoracotomy procedure. The RISS block involves injecting local anesthetic between the rhomboid major muscle and the intercostal muscles, while the SAPB targets the lateral cutaneous branches of the thoracic intercostal nerves near the serratus anterior muscle. Both techniques use bupivacaine as the anesthetic, and the procedures are performed with a high-frequency linear ultrasound probe to ensure accurate placement. Throughout the study, participants will be closely monitored for opioid consumption in the 24 hours after surgery, as well as pain levels at rest and during coughing at multiple time points up to 24 hours postoperatively. Additional measurements include heart rate, blood pressure, oxygen levels, hospital stay length, patient satisfaction, and potential side effects like nausea or local anesthetic toxicity. The total study duration covers surgery and 24 hours of postoperative observation, with detailed data collected to assess the effectiveness and safety of each block method.

CONDITIONS

Brief Title

Rhomboid Intercostal Sub Serratus Plane Block Versus Serratus Anterior Plane Block in Thoractomy

Who Can Participate

Age: 18Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18-70 years
  • Scheduled for unilateral thoracotomy surgery
  • American Society of Anesthesiologists (ASA) physical status I-III
  • Candidates for general anesthesia
  • No history of severe allergies to local anesthetics or medications used during the procedure
Not Eligible

You will not qualify if you...

  • ASA physical status class IV or higher
  • Obesity with body mass index (BMI) of 35 or greater
  • Uncontrolled cardiovascular diseases
  • Neurological deficits or cardiopulmonary, liver, kidney, or metabolic diseases
  • Use of anticoagulants or any drug allergies
  • Emergency or repeat surgeries
  • Systemic infections or infections at the injection site
  • Psychiatric illnesses such as schizophrenia, bipolar disorder, or uncontrolled anxiety or depression
  • Narcotic dependency

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Day of surgery

Participants undergo thoracotomy surgery with either the rhomboid intercostal sub serratus plane block or the serratus anterior plane block performed under general anesthesia for pain management.

1 surgical procedure visit

Post-operative Follow-up

Duration - 24 hours postoperatively

Participants are monitored for pain levels, opioid consumption, and side effects after surgery for up to 24 hours.

Multiple assessments within 24 hours post-surgery

Trial Site Locations

Total: 1 location

1

Fayoum University hospital

El Fayoum Qesm, Faiyum Governorate, Egypt, 63514

Actively Recruiting

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Research Team

E

Emad El Mohamed Abd El-Razek, M.Sc.

Y

Yasser S Mostafa, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Published Research Related To This Trial

Evaluation of ultrasound-guided rhomboid intercostal nerve block for postoperative analgesia in breast cancer surgery: a prospective, randomized controlled trial.

Başak Altıparmak, Melike Korkmaz Toker, Ali Ihsan Uysal...

https://pubmed.ncbi.nlm.nih.gov/32079739

Serratus anterior plane block and erector spinae plane block in postoperative analgesia in thoracotomy: A randomised controlled study.

Mohamed Elsayed Hassan, Mohamed Abd Alfattah Wadod

https://pubmed.ncbi.nlm.nih.gov/35359482