Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
FEMALE
NCT07390448

Rhomboid Intercostal Sub-serratus Plane Blocks and Erector Spinae Plane Block in Mastectomy Surgeries

Led by National Cancer Institute, Egypt · Updated on 2026-02-10

40

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Acute post-mastectomy pain can cause adverse impacts on the patients as delayed discharge from post-operative recovery area, impairs pulmonary and immune functions, increases risk of ileus, thromboembolism, myocardial infarction and may lead to increased length of hospital stay. It is also an important factor leading to the development of chronic post mastectomy pain syndrome (PMPS) in almost half of the patients. Various regional anesthetic techniques have been described for postoperative pain relief after mastectomy, for example, thoracic epidural anesthesia, intercostal nerve block, paravertebral block, serratus anterior plane block, and pectoral nerve I and II blocks. All of them offer satisfactory pain relief after mastectomy. Erector spinae plane block is a novel para-spinal regional anesthesia technique, , promises to provide effective visceral as well as somatic analgesia after carcinoma of the breast surgeries. The ultrasound-guided rhomboid intercostal block sub-serratus plane block (RISS) is a novel analgesic technique The RISS block anesthetizes the lateral cutaneous branches of the thoracic intercostal nerves and can be used in multiple clinical settings for chest wall and upper abdominal analgesia

CONDITIONS

Official Title

Rhomboid Intercostal Sub-serratus Plane Blocks and Erector Spinae Plane Block in Mastectomy Surgeries

Who Can Participate

Age: 18Years - 60Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients with breast cancer
  • ASA class II or III
  • Age between 18 and 60 years
  • Body mass index (BMI) greater than 20 kg/m2 and less than 35 kg/m2
  • Scheduled for elective breast cancer surgery including modified radical mastectomy or conservative breast surgery with axillary dissection
Not Eligible

You will not qualify if you...

  • Patient refusal to participate
  • Age less than 18 years or greater than 65 years
  • Body mass index (BMI) less than 20 kg/m2 or greater than 35 kg/m2
  • Presence of major medical conditions
  • Pregnancy or breastfeeding

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Cancer Institute - Cairo University

Cairo, Egypt, 11796

Actively Recruiting

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Research Team

A

Ayman Sharawy Abdelrahman Aboul Nasr, MD

CONTACT

A

Asmaa Elsayed Khalil Elmoghazy, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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