Actively Recruiting
Rifampicin Resistance in S. Aureus During and After Treatment for Latent Tuberculosis
Led by Region Skane · Updated on 2024-07-15
100
Participants Needed
1
Research Sites
269 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Two commonly used treatments for latent tuberculosis infection are either 4 months rifampicin or 6-9 months isoniazid. The invistigators will study the risk of acquisition of rifampicin resistance in commensal Staphylococcus aureus in persons treated with rifampicin versus in persons treated with isoniazide. Through repeated swab cultures before, during, and after treatment the investigators will also investigate potential accumulation of mutations associated with rifampicin resistance over time. Finally, household contacts to persons with rifampicin-resistant S. aureus will be examined to investigate whether onward transmission of rifampicin-resistant S. aureus occurs within households.
CONDITIONS
Official Title
Rifampicin Resistance in S. Aureus During and After Treatment for Latent Tuberculosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with latent tuberculosis
- Prescribed either 4 months rifampicin or 6-9 months isoniazid
- Provided informed consent
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Skåne University Hospital
Malmö, Sweden, 20502
Actively Recruiting
Research Team
A
Anton Reepalu, PhD
CONTACT
A
Anna Nilsson, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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