Actively Recruiting
Right Versus Left Thoracic Surgical Approaches for Siewert II Gastroesophageal Junction Adenocarcinoma
Led by Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Updated on 2024-10-16
236
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To explore the 5-year overall survival (OS) of right versus left thoracic surgical approaches for patients with locally advanced Siewert II gastroesophageal junction adenocarcinoma treated by neoadjuvant chemotherapy
CONDITIONS
Official Title
Right Versus Left Thoracic Surgical Approaches for Siewert II Gastroesophageal Junction Adenocarcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed gastroesophageal adenocarcinoma
- R0 resectable Siewert II, cT2-3N0-3M0 (AJCC V8 TNM classification)
- Performance status of 0 or 1 on the ECOG Performance Scale
- Age between 18 and 80 years
- Estimated survival of at least 6 months
- Ability and willingness to provide written informed consent
- Adequate organ function
- Negative pregnancy test within 7 days before enrollment for females of childbearing potential
- No prior systemic or local treatment for esophageal cancer
You will not qualify if you...
- History of other malignant tumors
- Previous upper abdominal surgery (excluding cholecystectomy)
- Bleeding, perforation, or obstruction requiring emergency surgical treatment
- Severe heart, lung, liver, or kidney dysfunction deemed unsuitable for operation
- Hydrothorax or ascites requiring therapeutic puncture or drainage
- Participation in another clinical study within the last month
- History of psychoactive drug abuse, alcoholism, or drug abuse
- Inability or unwillingness to bear inspection and treatment expenses
- Any other condition the researcher deems exclusionary
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Cancer Hospital Chinese Academy of Medical Sciences
Beijing, China
Actively Recruiting
Research Team
Y
Yin Li, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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