Actively Recruiting

Phase Not Applicable
Age: 14Years - 19Years
All Genders
ID06581536

Rigorous Evaluation of Yes and Know, a Fully Virtual Intervention Integrating Group-based Education With Digital Tools to Improve Youth Sexual Health and Well-Being

Led by ETR Associates · Updated on 2026-05-14

1200

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

E

ETR Associates

Lead Sponsor

U

University of California, San Francisco

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the Yes and Know program, a virtual sexual health education intervention for youth aged 14 to 19 years. This study is a two-arm randomized controlled trial involving about 1,200 participants to compare the effectiveness of the Yes and Know curriculum against a nutrition education program in improving sexual and reproductive health outcomes. The trial focuses on reducing unprotected sex and enhancing knowledge, attitudes, self-efficacy, and use of reproductive health services among adolescents. Participants will be randomly assigned to one of two groups. The treatment group will receive the Yes and Know program, which includes nine weekly 60-minute synchronous virtual sessions plus additional asynchronous online activities, covering sexual and reproductive health, healthy relationships, life skills, and educational success. The comparison group will receive a nutrition-focused program with a similar format and duration, concentrating on adolescent nutrition and wellness. Throughout the study, participants will complete brief online surveys at the start, and at 3 and 12 months after the intervention sessions. Researchers will assess outcomes such as rates of unprotected sex at 12 months, and improvements in sexual health knowledge, attitudes toward consent, relationship communication skills, condom use self-efficacy, and health service use. The study is conducted virtually with group sessions and online resources, lasting at least 12 months of follow-up per participant.

CONDITIONS

Brief Title

Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth

Who Can Participate

Age: 14Years - 19Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 14 to 19 years
  • English speaking
Not Eligible

You will not qualify if you...

  • Anyone not meeting inclusion criteria (ages 14-19 and English speaking).

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (virtual)

Outpatient Treatment

Duration - Approximately 9 weeks

Participants attend nine 60-minute synchronous virtual group sessions focusing on life skills, sexual and reproductive health, or nutrition education, with access to supplemental online resources and activities.

Weekly virtual sessions for 9 weeks

Follow-up

Duration - Up to 12 months post intervention

Participants complete assessments evaluating sexual health and related behaviors up to 12 months post intervention.

Assessments at 3 months and 12 months post intervention (virtual)

Trial Site Locations

Total: 1 location

1

ETR Associates

Watsonville, California, United States, 95076

Actively Recruiting

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Research Team

R

Rebecca A Braun, DrPH, MPH

P

Pamela K Anderson, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Published Research Related To This Trial