Actively Recruiting

Age: 18Years +
All Genders
NCT06409832

RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment

Led by University of Florence · Updated on 2026-01-21

100

Participants Needed

2

Research Sites

179 weeks

Total Duration

On this page

Sponsors

U

University of Florence

Lead Sponsor

I

IRCCS National Neurological Institute "C. Mondino" Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of rimegepant as preventive migraine treatment in a cohort of episodic or chronic migraine patients.

CONDITIONS

Official Title

RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of migraine without aura, migraine with aura, or chronic migraine according to the 3rd edition of the International Classification of Headache Disorder (ICHD-III)
  • At least 4 monthly migraine days
  • Good compliance to study procedures
  • Availability of headache diary at least of the preceding months before enrollment
Not Eligible

You will not qualify if you...

  • Subjects with contraindications for use of gepants
  • Concomitant diagnosis of medical diseases and/or comorbidities that might interfere with study assessments
  • Medical comorbidities that could interfere with study results
  • Pregnancy and breastfeeding
  • Changes in preventive treatments in the month before the first administration of rimegepant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

SOD Centro Cefalee e Farmacologia Clinica, AOU Careggi

Florence, Italy, 50134

Actively Recruiting

2

IRCCS National Neurological Institute "C. Mondino" Foundation

Pavia, Italy, 27100

Actively Recruiting

Loading map...

Research Team

L

Luigi F Iannone, MD

CONTACT

R

Roberto De Icco, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment | DecenTrialz