Actively Recruiting
RIR and the Impact on Clinical Outcomes in Patients Undergoing PCI
Led by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Updated on 2023-12-22
1408
Participants Needed
1
Research Sites
295 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Coronary heart disease (CAD) is caused by myocardial ischemia, hypoxia or necrosis due to coronary artery stenosis, spasm or obstruction. Although standard drug therapy can greatly improve the prognosis of patients with CAD after percutaneous coronary interventions (PCI), these patients are still at high risk of major adverse cardiovascular events (MACE). At present, the concept of residual inflammation risk (RIR) has aroused widespread concern. RIR is an important independent risk in patients with CAD. Foreign studies indicate that hsCRP ≥ 2mg / L is the definition standard of RIR in CAD. In China, there is no defined value of RIR for patients undergoing PCI, and the incidence of RIR has not been investigated clearly. At the same time, the impact of dynamic changes of hsCRP on MACE in PCI population needs to be further explored. Therefore, in this study, we plan to recruit patients undergoing PCI, and observe the impact of RIR by serial hsCRP measurements on the prognosis of these patients followed up for 5 years.
CONDITIONS
Official Title
RIR and the Impact on Clinical Outcomes in Patients Undergoing PCI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants who understand and sign the informed consent form voluntarily;
- Age ≥ 18 years old and ≤ 80 years old, regardless of sex;
- The hospitalized patients with coronary heart disease undergoing PCI;
- Complete all planned PCI during hospitalization
You will not qualify if you...
- Patients do not receive standardized treatment according to guidelines after being diagnosed with coronary heart disease;
- Uncontrolled infectious diseases during the screening period;
- In the screening stage, patients with immune diseases or immune-related diseases such as systemic lupus erythematosus, asthma, inflammatory bowel disease, gout, malignant tumor and so on;
- Long-term use of non-steroidal anti-inflammatory drugs, hormones, immunomodulatory and chemotherapeutic drugs during the study period;
- Surgical or interventional treatment was performed within 3 months before the screening period;
- Pregnant women, lactating women or women of childbearing age who do not use effective contraceptives;
- Participated in other clinical trials within 3 months before the screening period;
- The researchers determined that other conditions in which the patient was not suitable to participate in the clinical trial.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430022
Actively Recruiting
Research Team
M
Miao Yu, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here