Actively Recruiting
Rise & Shine: Promoting Sleep Quality in Chronic Stroke With Exercise
Led by University of British Columbia · Updated on 2026-04-13
62
Participants Needed
1
Research Sites
163 weeks
Total Duration
On this page
Sponsors
U
University of British Columbia
Lead Sponsor
V
Vancouver Coastal Health Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
health problems, such as heart disease, diabetes, cognitive impairment, and dementia. After a person suffers a stroke, they often experience difficulties in getting a good night's sleep. Approximately half of stroke survivors have insomnia, or have trouble falling and/or staying asleep. Poor sleep quality among stroke survivors increases the risk of recurrent stroke by 3-fold and the risk of early death by 76%. Hence, stroke survivors need strategies to promote better sleep. Fortunately, evidence shows that sleep quality can be improved with exercise, even among those who struggle with insomnia. Whether exercise training can improve sleep quality in adults with chronic stroke (i.e., at least 12 months has passed since their stroke) and poor sleep quality is not known. In addition, it is unknown if improved sleep is associated with improved outcomes in those with chronic stroke. This study will specifically evaluate the effect of twice-weekly targeted exercise training on sleep quality over a 6-month period in persons with chronic stroke and poor sleep quality. This study will also evaluate the effect of exercise on the following outcomes: 1) sleep structure; 2) fatigue; 3) daytime sleepiness; 4) mood; 5) physical function and capacity; 6) thinking abilities; 7) heart health; and 8) quality of life. Finally, this study will examine how changes in sleep quality may be related to changes in these outcomes. Our proposed research is timely as the importance of sleep to recovery, health, and wellbeing post-stroke is increasingly recognized.
CONDITIONS
Official Title
Rise & Shine: Promoting Sleep Quality in Chronic Stroke With Exercise
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 55 years or older
- Had an ischemic or hemorrhagic stroke at least 12 months prior
- Poor sleep quality defined by sleep efficiency ≤ 85% and PSQI global score > 5
- Baseline MMSE score ≥ 22/30 and MoCA score ≥ 19/30
- Community-dwelling
- Able to comply with assessments, classes, and study procedures
- Able to read, write, and speak English with acceptable vision and hearing
- Not starting or stable on fixed dose of sleep-impacting medication for at least 6 months before and during the 26-week period
- Able to walk minimum six meters with rest intervals, with or without assistive devices
- Have activity tolerance of 60 minutes with rest intervals
- Not currently participating in regular therapy or progressive exercise programs
- Cleared to safely engage in exercise by PAR-Q+63 and written confirmation from family or study physicians
You will not qualify if you...
- Diagnosed with obstructive sleep apnea (OSA) and not using CPAP, or potential undiagnosed OSA with AHI > 20
- Have restless leg syndrome
- Diagnosed with any type of dementia
- Diagnosed with other neurodegenerative or neurological conditions (e.g., Parkinson's disease)
- Currently enrolled or planning to participate in a clinical drug or exercise trial concurrent to this study
- At high risk for cardiac complications during exercise or unable to self-regulate activity
- Have significant peripheral neuropathy or severe musculoskeletal or joint disease impairing mobility
- Have aphasia preventing phone communication
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Vancouver Coastal Health Research Institute Research Pavilion
Vancouver, British Columbia, Canada, V5Z 1L8
Actively Recruiting
Research Team
T
Teresa Liu-Ambrose, PhD
CONTACT
R
Ryan Stein, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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