Actively Recruiting

Phase Not Applicable
Age: 55Years +
All Genders
NCT06847074

Rise & Shine: Promoting Sleep Quality in Chronic Stroke With Exercise

Led by University of British Columbia · Updated on 2026-04-13

62

Participants Needed

1

Research Sites

163 weeks

Total Duration

On this page

Sponsors

U

University of British Columbia

Lead Sponsor

V

Vancouver Coastal Health Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

health problems, such as heart disease, diabetes, cognitive impairment, and dementia. After a person suffers a stroke, they often experience difficulties in getting a good night's sleep. Approximately half of stroke survivors have insomnia, or have trouble falling and/or staying asleep. Poor sleep quality among stroke survivors increases the risk of recurrent stroke by 3-fold and the risk of early death by 76%. Hence, stroke survivors need strategies to promote better sleep. Fortunately, evidence shows that sleep quality can be improved with exercise, even among those who struggle with insomnia. Whether exercise training can improve sleep quality in adults with chronic stroke (i.e., at least 12 months has passed since their stroke) and poor sleep quality is not known. In addition, it is unknown if improved sleep is associated with improved outcomes in those with chronic stroke. This study will specifically evaluate the effect of twice-weekly targeted exercise training on sleep quality over a 6-month period in persons with chronic stroke and poor sleep quality. This study will also evaluate the effect of exercise on the following outcomes: 1) sleep structure; 2) fatigue; 3) daytime sleepiness; 4) mood; 5) physical function and capacity; 6) thinking abilities; 7) heart health; and 8) quality of life. Finally, this study will examine how changes in sleep quality may be related to changes in these outcomes. Our proposed research is timely as the importance of sleep to recovery, health, and wellbeing post-stroke is increasingly recognized.

CONDITIONS

Official Title

Rise & Shine: Promoting Sleep Quality in Chronic Stroke With Exercise

Who Can Participate

Age: 55Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 55 years or older
  • Had an ischemic or hemorrhagic stroke at least 12 months prior
  • Poor sleep quality defined by sleep efficiency ≤ 85% and PSQI global score > 5
  • Baseline MMSE score ≥ 22/30 and MoCA score ≥ 19/30
  • Community-dwelling
  • Able to comply with assessments, classes, and study procedures
  • Able to read, write, and speak English with acceptable vision and hearing
  • Not starting or stable on fixed dose of sleep-impacting medication for at least 6 months before and during the 26-week period
  • Able to walk minimum six meters with rest intervals, with or without assistive devices
  • Have activity tolerance of 60 minutes with rest intervals
  • Not currently participating in regular therapy or progressive exercise programs
  • Cleared to safely engage in exercise by PAR-Q+63 and written confirmation from family or study physicians
Not Eligible

You will not qualify if you...

  • Diagnosed with obstructive sleep apnea (OSA) and not using CPAP, or potential undiagnosed OSA with AHI > 20
  • Have restless leg syndrome
  • Diagnosed with any type of dementia
  • Diagnosed with other neurodegenerative or neurological conditions (e.g., Parkinson's disease)
  • Currently enrolled or planning to participate in a clinical drug or exercise trial concurrent to this study
  • At high risk for cardiac complications during exercise or unable to self-regulate activity
  • Have significant peripheral neuropathy or severe musculoskeletal or joint disease impairing mobility
  • Have aphasia preventing phone communication

AI-Screening

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Trial Site Locations

Total: 1 location

1

Vancouver Coastal Health Research Institute Research Pavilion

Vancouver, British Columbia, Canada, V5Z 1L8

Actively Recruiting

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Research Team

T

Teresa Liu-Ambrose, PhD

CONTACT

R

Ryan Stein, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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