Actively Recruiting

Phase 4
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT07203287

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

Led by The University of Texas Medical Branch, Galveston · Updated on 2026-02-23

490

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer is "The use of Cisatracurium with neostigmine leads to less post-operative pulmonary complications than Rocuronium with sugammadex."

CONDITIONS

Official Title

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able and willing to provide and sign informed consent
  • Between 18 and 80 years of age
  • Have chronic kidney disease defined by glomerular filtration rate
  • Surgery requires general anesthesia with endotracheal intubation and neuromuscular blockade
Not Eligible

You will not qualify if you...

  • Under 18 years old
  • Over 80 years old
  • Have end stage renal disease
  • Require dialysis
  • Presenting for renal transplantation
  • Pregnant female
  • Currently in the correctional system
  • Urgent or emergent procedure
  • Surgery requires intubation after operation
  • Allergy to Rocuronium, Sugammadex, Cisatracurium, or Neostigmine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Texas Medical Branch

Galveston, Texas, United States, 77554

Actively Recruiting

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Research Team

M

Michael Kinsky, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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