Actively Recruiting
Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer
Led by City of Hope Medical Center · Updated on 2026-03-13
240
Participants Needed
1
Research Sites
275 weeks
Total Duration
On this page
Sponsors
C
City of Hope Medical Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial evaluates the usefulness of various risk assessment tests, including Helicobacter pylori (H. pylori) breath testing, questionnaires, and endoscopies for identifying participants at high risk for stomach cancer. H. pylori is a bacteria that causes stomach inflammation and ulcers in the stomach. People with H. pylori infections may be more likely to develop cancer in the stomach. H. pylori breath testing can help identify the presence of H. pylori infection in a participant and help identify if the participant may be at a higher risk of developing stomach cancer. An endoscopy uses a thin, flexible lighted tube that is inserted inside the esophagus, stomach, and first part of the small intestine. This allows the doctor to see and look for abnormal areas that may need to be biopsied. Risk assessment including H. pylori evaluation, questionnaires, and endoscopies may help identify participants at high risk for stomach cancer and may be a useful screening tool for earlier stomach cancer diagnosis.
CONDITIONS
Official Title
Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Documented informed consent of the participant and/or legally authorized representative
- Assent obtained when appropriate per institutional guidelines
- Age between 40 and 80 years
- Identify as a racial minority: Asian, Hispanic, or Black American
- Willingness to provide blood samples and undergo upper endoscopy
You will not qualify if you...
- Identify as Non-Hispanic White
- History of gastric cancer
- Known premalignant lesions of the stomach
- History of upper endoscopy within 2 years
- Women of childbearing potential who are pregnant or nursing
- Employees under direct or indirect supervision of the principal investigator, coinvestigator, or study manager
- Direct study team members
AI-Screening
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Trial Site Locations
Total: 1 location
1
City of Hope Medical Center
Duarte, California, United States, 91010
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
SCREENING
Number of Arms
3
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