Pilot Study to Assess Stomach Cancer Risk Using H. pylori Testing, Questionnaires, and Endoscopy in Adults 40 to 80 Years Focusing on Asian, Hispanic, and Black American Communities for Early Detection and Prevention

What this Trial Is About

Researchers are evaluating various risk assessment methods to identify people at high risk for stomach cancer. This study focuses on tests such as Helicobacter pylori H. pylori breath testing, questionnaires, and endoscopies. H. pylori is a bacteria linked to stomach inflammation, ulcers, and may increase the risk of stomach cancer. The research aims to determine how well these assessments work in diverse ethnic populations and to explore community outreach feasibility for early detection and prevention of gastric cancer. Participants start with a baseline risk assessment that includes questionnaires, blood sample collection, and an H. pylori breath test. Those identified as high-risk join a group that may receive an esophagogastroduodenoscopy EGD with possible tissue biopsy within three months and complete annual questionnaires for up to three years. Participants not at high risk continue with annual questionnaires for three years and may have an EGD at year two. Throughout the study, participants undergo regular evaluations including questionnaires and medical tests to monitor their stomach health. The study tracks how many people are found to be at high risk for gastric cancer and follows participants annually for three years. This ongoing monitoring helps researchers understand risk factors and the usefulness of these assessments in early stomach cancer detection and prevention.

Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer