Actively Recruiting

Age: 18Years - 65Years
All Genders
NCT06341933

Risk Factors for AKI in Patients Undergoing VATS for Pulmonary Resection

Led by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · Updated on 2025-01-30

100

Participants Needed

1

Research Sites

87 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to investigate the potential factors contributing to the development of Acute Kidney Injury (AKI) in patients undergoing pulmonary resection with Video Assisted Thoracoscopic Surgery (VATS) for lung malignancy. The study will focus on demographic data, laboratory parameters, perioperative fluid management, and haemodynamics. The research will be conducted at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital. The study will involve patients who have given informed consent and will undergo VATS with standard anaesthesia monitoring. Anaesthesia management will follow our routine protocol in our clinic. Patients will be divided into two groups based on whether they have a more than 25% decrease in estimated glomerular filtration rate (t-GFH) and/or a 1.5-fold increase in serum creatinine and/or a 6-hour urine volume of less than 0.5 ml/kg/h. The patients will be divided into two groups based on this definition, and the risk factors between these groups will be analysed. The preoperative routine blood values, demographic data (age, gender, height, weight, and BMI), ASA physical status, smoking and alcohol habits, comorbidities, and regular medication use will be recorded. Intraoperative urine output and haemodynamic parameters will also be monitored. Routine blood gas analysis, blood urea nitrogen (BUN), glomerular filtration rate (GFR), albumin, haemoglobin, sodium, potassium, chlorine, and magnesium will be measured and recorded, along with urine output and t-GFH. Patients will be evaluated in the hospital on the day the surgeon calls for a postoperative check-up and on the 30th postoperative day to see if there are any complications.

CONDITIONS

Official Title

Risk Factors for AKI in Patients Undergoing VATS for Pulmonary Resection

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Between 18 and 65 years of age
  • American Society of Anesthesiologists (ASA) physical status 1 to 3
  • Undergoing elective wedge resection, segmentectomy, or lobectomy with VATS for lung malignancy
Not Eligible

You will not qualify if you...

  • Body mass index (BMI) less than 18.5 kg/m2 or greater than 35 kg/m2
  • Impaired renal function with serum creatinine above 1.3 mg/dL for men or 1.1 mg/dL for women
  • Received radiocontrast material before surgery
  • Diagnosed and treated for congestive heart failure
  • History of pulmonary edema
  • Long-term use (over 30 days) of steroids or non-steroidal anti-inflammatory drugs
  • Intubated in intensive care unit
  • Requires massive blood transfusion during surgery
  • Missing data for required study parameters

AI-Screening

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Trial Site Locations

Total: 1 location

1

Ankara Atatürk Sanatorium Training and Research Hospital

Ankara, Keçiören, Turkey (Türkiye), 06290

Actively Recruiting

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Research Team

A

Ali ALAGÖZ, professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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