Actively Recruiting
Risk Factors for Colonization or Infection With Carbapenem-Resistant Enterobacteriaceae in PICU Hospitalized Children at Children's Hospital of Fudan University
Led by Children's Hospital of Fudan University · Updated on 2026-03-16
536
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research focuses on children hospitalized in the Pediatric Intensive Care Unit (PICU) at Children's Hospital of Fudan University between January 2018 and December 2019. It aims to understand the risk factors and microbiologic characteristics of infections or colonization with Carbapenem-Resistant Enterobacteriaceae (CRE), a group of bacteria resistant to certain antibiotics. The study is retrospective, reviewing past medical records to gather data on this serious infection in a high-risk pediatric population. Children in the study are grouped based on their clinical culture results during their PICU stay: those without CRE, those colonized with CRE but without symptoms, and those infected with CRE showing clinical symptoms. CRE is defined according to CDC criteria as bacteria resistant to specific antibiotics like imipenem, meropenem, or ertapenem. The study collects clinical and demographic data from electronic health records to analyze these groups. Participants' involvement includes reviewing medical records to track outcomes such as mortality within 28 days after PICU discharge and the length of PICU stay within the same period. The study does not involve new treatments but monitors past hospital data to identify factors linked to CRE colonization or infection. The research extends over a timeframe from January 2018 to December 2019 and is sponsored by Children's Hospital of Fudan University.
CONDITIONS
Brief Title
Risk Factors for Colonization or Infection With Carbapenem-Resistant Enterobacteriaceae in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children hospitalized in the Pediatric Intensive Care Unit (PICU) of Children's Hospital of Fudan University from January 2018 to December 2019
You will not qualify if you...
- Discharged from PICU within 48 hours
- Positive culture for Carbapenem-Resistant Enterobacteriaceae (CRE) before admission
- Incomplete clinical and demographic data
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to duration of PICU hospitalization
Participants who are hospitalized in the Pediatric Intensive Care Unit are observed and clinical and demographic data are collected from electronic health records during their stay.
Data collected from clinical records during PICU stay
Duration - 28 days after PICU discharge
After discharge from the PICU, participants are followed for up to 28 days to monitor mortality and length of stay outcomes.
Follow-up data collection for up to 28 days post-discharge
Trial Site Locations
Total: 1 location
1
Children's Hospital of Fudan University
Shanghai, Shanghai Municipality, China
Actively Recruiting
Research Team
G
Gangfeng Yan
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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