Actively Recruiting
Risk Factors of Extubation Failure in PICU Patients
Led by Sohag University · Updated on 2024-08-16
100
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Up to 20% of MV patients experience EF \[10\]. EF is defined as the need to reinsert the endotracheal tube to resume MV in patients extubated for less than 48 hours. It has high rates of morbidity and mortality, prolongs the duration of MV and thus causes a longer stay in the PICU and risk of complications such as the need for tracheostomy, the incidence of pneumonia and pulmonary damage, and finally, costs increase as well and death \[10, 11\] .
CONDITIONS
Official Title
Risk Factors of Extubation Failure in PICU Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient is less than 18 years old and admitted to PICU
- Patient has been on mechanical ventilation through an endotracheal tube for more than 12 hours
- Patient meets weaning criteria including evidence of reversal of respiratory failure cause, adequate oxygenation (PaO2/FIO2 ratio ≥ 200, FIO2 ≤ 0.40, PaO2 ≥ 60, PaCO2 ≤ 60, PEEP ≤ 5 cmH2O), pH ≥ 7.25, respiratory rate ≤ 45 bpm, heart rate ≤ 140 bpm, rapid shallow breathing index (RSBI) ≤ 8 breaths/min/ml/kg
- Patient is hemodynamically stable with no or minimal vasopressors or inotropes
- Patient has appropriate level of consciousness, no continuous sedation infusion or neuromuscular blockers, is afebrile, has hemoglobin ≥ 7.5 g/dl and no evidence of hemorrhage
You will not qualify if you...
- Patient is younger than 30 days old
- Patient has a tracheostomy
- Patient died while on mechanical ventilation within 12 hours
- Patient had unplanned extubation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sohag University Hospitals
Sohag, Egypt
Actively Recruiting
Research Team
M
mariam raafat helmy, postgraduate
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here